Glukoza-1-fosfat uridililtransferaza

Glukoza-1-fosfat uridililtransferaza
Glukoza-1-fosfat uridililtransferaza oktamer, Human
Identifikatori
EC broj	2.7.7.9
CAS broj	9026-22-6
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Glukoza-1-fosfat uridililtransferaza (EC 2.7.7.9, UDP glukozna pirofosforilaza, glukoza-1-fosfatna uridililtransferaza, UDPG fosforilaza, UDPG pirofosforilaza, uridin 5'-difosfoglukoza pirofosforilaza, uridin difosfoglukozna pirofosforilaza, uridin difosfat-D-glukozna pirofosforilaza, uridin-difosfat glukozna pirofosforilaza) je enzim sa sistematskim imenom UTP:alfa-D-glukoza-1-fosfat uridililtransferaza.^{[1][2][3][4][5]} Ovaj enzim katalizuje sledeću hemijsku reakciju

UTP + alfa-D-glukoza 1-fosfat ${\displaystyle \rightleftharpoons }$ difosfat + UDP-glukoza

Reference

1. Kalckar, H.M. (1953). „The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides”. Biochim. Biophys. Acta 12: 250-264. PMID 13115434. 
2. Kamogawa, A. and Kurahashi, K. (1965). „Purification and properties of uridinediphosphate glucose pyrophosphorylase from Escherichia coli K12”. J. Biochem. (Tokyo) 57: 758-765. PMID 4284510. 
3. Lobelle-Rich, P.A. and Reeves, R.E. (1983). „Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica”. Mol. Biochem. Parasitol. 7: 173-182. PMID 6304512. 
4. Smith, E.E.B. and Mills, G.T. (1955). „The uridyl transferase of mammary gland”. Biochim. Biophys. Acta 18: 152-152. PMID 13260264. 
5. Turnquist, R.L., Gillett, T.A. and Hansen, R.G. (1974). „Uridine diphosphate glucose pyrophosphorylase. Crystallization and properties of the enzyme from rabbit liver and species comparisons”. J. Biol. Chem. 249: 7695-7700. PMID 4436332. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH UTP---glucose-1-phosphate+uridylyltransferase