Kanadin

Kanadin
Identifikacija
CAS registarski broj	522-97-4
PubChem[1][2]	21171
ChemSpider[3]	19910
ChEMBL[4]	CHEMBL490533^Y
Jmol-3D slike	Slika 1
SMILES O1c2c(OC1)cc3c(c2)CCN5[C@H]3Cc4ccc(OC)c(OC)c4C5
InChI InChI=1S/C20H21NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3/t16-/m0/s1^Y Kod: VZTUIEROBZXUFA-INIZCTEOSA-N^Y InChI=1/C20H21NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3/t16-/m0/s1 Kod: VZTUIEROBZXUFA-INIZCTEOBL
Svojstva
Molekulska formula	C20H21NO4
Molarna masa	339,38504
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
Infobox references

Kanadin je protoberberinski alkaloid^[5][6] koji deluje kao blokator kalcijumskog kanala.

Reference

1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
5. Cech NB, Junio HA, Ackermann LW, Kavanaugh JS, Horswill AR (2012-07-18). „Quorum Quenching and Antimicrobial Activity of Goldenseal (Hydrastis canadensis) against Methicillin-Resistant Staphylococcus aureus (MRSA)”. Planta Med.. 
6. Correché ER, Andujar SA, Kurdelas RR, Gómez Lechón MJ, Freile ML, Enriz RD (2008-04-01). „Antioxidant and cytotoxic activities of canadine: biological effects and structural aspects”. Bioorg Med Chem. 16: 3641-51. 

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