Serin-tRNK ligaza
| Serin-tRNK ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.1.1.11 | ||||||||
| CAS broj | 9023-48-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Serin-tRNK ligaza (EC 6.1.1.11, seril-tRNK sintetaza, SerRS, seril-transfer ribonukleat sintetaza, seril-transfer RNK sintetaza, seril-transfer ribonukleinska kiselina sintetaza, serin translase) je enzim sa sistematskim imenom L-serin:tRNKSer ligaza (formira AMP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe prepoznaje tRNKSec, specijalnu tRNK za selenocistein.
- ↑ Katze, J.R. and Konigsberg, W. (1970). „Purification and properties of seryl transfer ribonucleic acid synthetase from Escherichia coli”. J. Biol. Chem. 245: 923-930. PMID 4906848.
- ↑ Makman, M.H. and Cantoni, G.L. (1965). „Isolation of seryl and phenylalanyl ribonucleic acid synthetases from baker's yeast”. Biochemistry 4: 1434-1442.
- ↑ Webster, L.T. and Davie, E.W. (1961). „Purification and properties of serine-activating enzyme from beef pancreas”. J. Biol. Chem. 236: 479-484. PMID 13783661.
- ↑ Ohama, T., Yang, D.C. and Hatfield, D.L. (1994). „Selenocysteine tRNA and serine tRNA are aminoacylated by the same synthetase, but may manifest different identities with respect to the long extra arm”. Arch. Biochem. Biophys. 315: 293-301. PMID 7986071.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.