Serratia marcescens nukleaza

Serratia marcescens nukleaza
Identifikatori
EC broj	3.1.30.2
CAS broj	9025-65-4
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Serratia marcescens nukleaza (EC 3.1.30.2, endonukleaza (Serratia marcescens), ječmena nukleaza, biljna nukleaza I, nukleatna endonukleaza) je enzim.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Endonukleolitičko razlaganje do 5'-fosfomononukleotidnih i 5'-fosfooligonukleotidnih krajnjih produkata

Ovaj enzim hidrolizuje dvostruke- ili jednostruke supstrate.

Reference

1. Mikulski, A.J. and Laskowski, M. (1970). „, Sr. Mung bean nuclease I. 3. Purification procedure and (3′) ω monophosphatase activity”. J. Biol. Chem. 245: 5026-5031. PMID 4319109. 
2. Stevens, A. and Hilmoe, R.J. (1960). „Studies on a nuclease from Azotobacter agilis. I. Isolation and mode of action”. J. Biol. Chem. 235: 3016-3022. 
3. Stevens, A. and Hilmoe, R.J. (1960). „Studies on a nuclease from Azotobacter agilis. II. Hydrolysis of ribonucleic and deoxyribonucleic acids”. J. Biol. Chem. 235: 3023-3027. 
4. Wechter, W.J., Mikulski, A.J. and Laskowski, M. (1968). „, Sr. Gradation of specificity with regard to sugar among nucleases”. Biochem. Biophys. Res. Commun. 30: 318-322. PMID 4296679. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Serratia+marcescens+nuclease