Claudio is an Italian and Spanish first name. In Portuguese, it is accented Cláudio. In Catalan and Occitan, it is Claudi, while in Romanian it is Claudiu.
Claudius was the name of an eminent Roman gens, the most important members of which were:
- Claudius, Emperor Tiberius Claudius Caesar Augustus Germanicus
- Appius Claudius Sabinus Regillensis (fl. 486 BC), founder of the family, originally a Sabine known as Attius Clausus.
- Appius Claudius Crassus (fl.450BC), public official, decemvir in 451 BC, appointed to codify the laws.
- Appius Claudius Caecus (fl.300BC), official orator, best known for the highway named after him, the Appian Way. Consul in 307 & 296.
- Claudius Gothicus (210–270), officer in the Roman army and a provincial governor
Claudio became a popular first name due to the spread of Christianity during the Middle Ages. Claudio is also used in Spanish and in Portuguese, accented as Cláudio. Notable people with the name include:
- Claudio Abbado (1933–2014), Italian conductor
- Claudio Acquaviva (1543–1615), Italian Jesuit
- Claudio Aranzadi (born 1946), Spanish engineer, businessman and politician
- Claudio Arrau (1903–1991), Chilean-born pianist
- Claudio Barragán (born 1964), Spanish footballer
- Claudio Beauvue (born 1988), French professional footballer from Guadeloupe who plays as a striker for Spanish club Celta de Vigo
- Claudio Biern Boyd (1940–2022), Spanish animator who founded the Spanish animation company BRB Internacional
- Claudio Bravo (born 1983), Chilean footballer
- Claudio Cabán (born 1963), Puerto Rican long-distance runner
- Claudio Caniggia (born 1967), Argentine retired footballer who played as forward or winger
- Claudio Castagnoli (born 1980), Swiss-born professional wrestler also known as Cesaro
- Claudio Chiappucci (born 1963), retired Italian professional cyclist
- Claudio Cirillo (born ?), Italian cinematographer, film Scent of a Woman We All Loved Each Other So Much (1974) and Crime Busters (1977)
- Claudio Donoso, Chilean forester
- Claudio García (born 1963), former Argentinian international footballer
- Claudio Gentile (born 1953), Italian football coach and former player
- Claudio Lolli (1950–2018), Italian singer-songwriter, poet and writer
- Claudio Magris (born 1939), Italian writer
- Claudio Marchisio (born 1986), Italian footballer
- Claudio Merulo (1533–1604), Italian composer and organist
- Claudio Monteverdi (1567–1643), Italian composer
- Claudio Patrignani (born 1959), Italian middle-distance runner
- Claudio Ranieri (born 1951), Italian football manager and player
- Claudio Sanchez (born 1978), lead singer and guitarist; of Coheed and Cambria
- Claudio Saracini (1586–1630), Italian composer
- Claudio Simonetti (born 1952), Italian composer
- Claudio Teehankee (1918–1989), Philippine Chief Justice
- Claudio Vitalone (1936–2008), Italian judge and politician
- Claudio Zulianello (born 1965), Argentine volleyball player
Cláudio is the Portuguese name derived from Claudius. Notable people with the name include:
- Cláudio César de Aguiar Mauriz (1940–1979), commonly known as Cláudio, Brazilian footballer
- Cláudio Christovam de Pinho (1922–2000), commonly known as Cláudio, Brazilian footballer
- Cláudio Mendes Prates (born 1965), commonly known as Cláudio, Brazilian footballer
- Luiz Cláudio Barros (born 1978), commonly known as Luiz Cláudio, Brazilian footballer
- Cláudio Roberto Siqueira Fernandes (born 1980), commonly known as Cláudio, Brazilian footballer
- Luís Cláudio Carvalho da Silva (born 1987), commonly known as Cláudio, Brazilian footballer