Irene is a 1940 American musical movie directed by Herbert Wilcox and was based on the 1919 musical of the same name by James Montgomery. It stars Anna Neagle, Ray Milland, Roland Young, Alan Marshal, May Robson, Billie Burke, Arthur Treacher, Marsha Hunt, Isabel Jewell and was distributed by RKO Radio Pictures. It was nominated for an Academy Award in 1941.