Eksodezoksiribonukleaza I
| Eksodezoksiribonukleaza I | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.11.1 | ||||||||
| CAS broj | 9037-46-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Eksodezoksiribonukleaza I (EC 3.1.11.1, Escherichia coli eksonukleaza I, E. coli eksonukleaza I, eksonukleaza I) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Eksonukleolitičko razlaganje u 3'- ka 5'- smeru čime se formiraju nukleozid 5'-fosfati
Ova enzim preferentno deluje na jednolačanu DNK.
Reference
[уреди | уреди извор]- ^ Blakesley, R.W.; Dodgson, J.B.; Nes, I.F.; Wells, R.D. (1977). „Duplex regions in single-stranded phiX174 DNA are cleaved by a restriction endonuclease from Haemophilus aegyptius”. J. Biol. Chem. 252: 7300—7306. PMID 71298.
- ^ Kelley, R.B.; Atkinson, M.R.; Huberman, J.A.; Kornberg, A. (1969). „Excision of thymine dimers and other mismatched sequences by DNA polymerases of Escherichia coli”. Nature. 224: 495—501.
- ^ Lehman, I.R. & Nussbaum, A.L. (1964). „The deoxyribonucleases of Escherichia coli. V. On the specificity of exonuclease I (phosphodiesterase)”. J. Biol. Chem. 239: 2628—2636. PMID 14235546.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Exodeoxyribonuclease+I на US National Library of Medicine Medical Subject Headings (MeSH)
