Pentagastrin
{{Drugbox-lat | IUPAC_name = (3S)-3- {[(1S)-1-karbamoil-2-feniletil]karbamoil}- 3-[(2S)-2-[(2S)-3-(1H-indol-3-il)-2-(3-{[(2-metilpropoksi)karbonil]amino}propanamido)propanamido]- 4-(metilsulfanil)butanamido]propanoinska kiselina | image = Pentagastrin.svg | width = | alt = | image2 = | width2 = | alt2 = | drug_name = Pentagastrin | caption =
| tradename = | Drugs.com = Monografija | MedlinePlus = | licence_EU = | licence_US = | DailyMedID = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | dependency_liability = | routes_of_administration =
| bioavailability = | protein_bound = | metabolism = | elimination_half-life = 10 minuta ili manje | excretion =
| CAS_number_Ref = 
| CAS_number = 5534-95-2
| CAS_supplemental =
| ATCvet =
| ATC_prefix = V04
| ATC_suffix = CG04
| ATC_supplemental =
| PubChem = 444007
| PubChemSubstance = 46507747
| IUPHAR_ligand = 870
| DrugBank_Ref =
| DrugBank = DB00183
| ChemSpiderID_Ref =
| ChemSpiderID = 392037
| UNII_Ref =
| UNII =
| KEGG_Ref =
| KEGG =
| ChEBI_Ref =
| ChEBI =
| ChEMBL_Ref =
| ChEMBL =
| synonyms =
|C=37 |H=49 |N=7 |O=9 |S=1
| molecular_weight = 767.891
| smiles = CSCC[C@H](NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)CCNC(=O)OCC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O
| StdInChI = 1S/C37H49N7O9S/c1-22(2)21-53-37(52)39-15-13-31(45)41-29(18-24-20-40-26-12-8-7-11-25(24)26)35(50)42-27(14-16-54-3)34(49)44-30(19-32(46)47)36(51)43-28(33(38)48)17-23-9-5-4-6-10-23/h4-12,20,22,27-30,40H,13-19,21H2,1-3H3,(H2,38,48)(H,39,52)(H,41,45)(H,42,50)(H,43,51)(H,44,49)(H,46,47)/t27-,28-,29-,30-/m0/s1
| StdInChIKey_Ref =
| StdInChI_comment =
| StdInChIKey = ALXRNCVIQSDJAO-KRCBVYEFSA-N
| StdInChI_Ref =
| density =
| melting_point = 229
| melting_high =
| melting_notes =
| boiling_point =
| boiling_notes =
| solubility =
| specific_rotation =
| sec_combustion =
}}
Pentagastrin je sintetički pentapeptid koji deluje poput gastrina pri parenteralnoj primeni. On stimuliše sekreciju želudačna kiseline i pepsina. Korišten je kao dijagnostičko sredstvo.[1][2][3]
Reference
[уреди | уреди извор]- ^ Weintraub HS, Rudolph A: Combination Therapy for Managing Difficult-to-Treat Patients With Stage 2 Hypertension: Focus on Valsartan-Based Combinations. Am J Ther. 2010 Jun 9. PMID 20535014
- ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.
- ^ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.
Spoljašnje veze
[уреди | уреди извор]
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
