Valin-tRNK ligaza

Valin-tRNK ligaza
Identifikatori
EC broj	6.1.1.9
CAS broj	9023-47-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Valin-tRNK ligaza (EC 6.1.1.9, valil-tRNK sintetaza, valil-transferna ribonukleatna sintetaza, valil-transferna RNK sintetaza, valil-transferna ribonukleinsko kiselinska sintetaza, valin transferna ribonukleatna ligaza, valinska translaza) je enzim sa sistematskim imenom L-valin:tRNKVal ligaza (formira AMP).^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + L-valin + tRNK^Val ${\displaystyle \rightleftharpoons }$ AMP + difosfat + L-valil-tRNK^Val

Reference

1. Berg, P., Bergmann, F.H., Ofengand, E.J. and Dieckmann, M. (1961). „The enzymic synthesis of amino acyl derivatives of ribonucleic acid. I. The mechanism of leucyl-, valyl-, isoleucyl- and methionyl ribonucleic acid formation”. J. Biol. Chem. 236: 1726—1734. CS1 одржавање: Вишеструка имена: списак аутора (веза)
2. Bergmann, F.H., Berg, P. and Dieckmann, M. (1961). „The enzymic synthesis of amino acyl derivatives of ribonucleic acid. II. The preparation of leucyl-, valyl-, isoleucyl- and methionyl ribonucleic acid synthetases from Escherichia coli”. J. Biol. Chem. 236: 1735—1740. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

• Valine---tRNA+ligase на US National Library of Medicine Medical Subject Headings (MeSH)