40S ribozomal protein S3

40S ribozomal protein S3
Uygun yapılar PDB Ortolog araması: PDBe RCSB PDB kimlik kodlarının listesi 1WH9, 4UG0, 4V6X, 5A2Q, 5AJ0, 3J7P, 4UJE, 4D5L, 3J7R, 4UJD, 4V5Z, 5FLX, 4D61, 4UJC
Tanımlayıcılar
Başka adlar	RPS3
Dış kimlikler	OMIM: 600454 MGI: 1350917 HomoloGene: 779 GeneCards: RPS3
Gen yerleşimi (İnsan) Krom. 11. Kromozom (insan)[1] Bant 11q13.4 Başlangıç 75,399,515 bç[1] Bitiş 75,422,280 bç[1]
RNA ekspresyonu deseni Daha çok ekspresyon verisi başvurusu
Gen ontolojisi Moleküler işlevi • tubulin binding • DNA N-glycosylase activity • small ribosomal subunit rRNA binding • iron-sulfur cluster binding • transcription factor binding • oxidized purine DNA binding • Hsp70 protein binding • lyase activity • enzyme binding • mRNA binding • structural constituent of ribosome • damaged DNA binding • ubiquitin-like protein conjugating enzyme binding • GO:0001948, GO:0016582 protein bağlanması • DNA-(apurinic or apyrimidinic site) endonuclease activity • oxidized pyrimidine DNA binding • endodeoxyribonuclease activity • protein kinase binding • supercoiled DNA binding • DNA binding • Hsp90 protein binding • microtubule binding • protein kinase A binding • RNA binding • kinase binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0032403 protein-containing complex binding • class I DNA-(apurinic or apyrimidinic site) endonuclease activity • class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity • oxidized purine nucleobase lesion DNA N-glycosylase activity Hücresel bileşeni • sitoplazma • Sitozol • Polizom • membrane • focal adhesion • ruffle membrane • mitokondri • Hücre iskeleti • hücre çekirdeği • ribozom • Çekirdekçik • extracellular exosome • Hücre zarı • İğ iplikleri • mitochondrial matrix • small ribosomal subunit • mitotic spindle • mitochondrial inner membrane • cytosolic small ribosomal subunit • Nükleoplazma • GO:0005578 Hücrelerarası madde • Endoplazmik retikulum • NF-kappaB complex • GO:0097483, GO:0097481 postsynaptic density • HnRNP • Sinaps Biyolojik süreci • Segregasyon • positive regulation of endodeoxyribonuclease activity • cellular response to DNA damage stimulus • positive regulation of microtubule polymerization • Hücre döngüsü • GO:0097285 apoptoz • negative regulation of translation • GO:0009373 regulation of transcription, DNA-templated • viral transcription • response to TNF agonist • positive regulation of apoptotic signaling pathway • GO:0001306 response to oxidative stress • transcription, DNA-templated • SRP-dependent cotranslational protein targeting to membrane • positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis • positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage • positive regulation of DNA N-glycosylase activity • positive regulation of JUN kinase activity • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • negative regulation of DNA repair • GO:1900404 positive regulation of DNA repair • positive regulation of NIK/NF-kappaB signaling • Hücre bölünmesi • spindle assembly • negative regulation of protein ubiquitination • GO:1901313 positive regulation of gene expression • translational initiation • regulation of translation • cellular response to hydrogen peroxide • protein biyosentezi • positive regulation of base-excision repair • GO:0100026 DNA onarımı • regulation of apoptotic process • rRNA processing • cytoplasmic translation • positive regulation of protein-containing complex assembly • positive regulation of interleukin-2 production • positive regulation of activated T cell proliferation • positive regulation of T cell receptor signaling pathway • positive regulation of NF-kappaB transcription factor activity • cellular response to tumor necrosis factor Kaynaklar:Amigo / QuickGO
Ortologlar
Türler	İnsan	Fare
Entrez	6188	27050
Ensembl	ENSG00000149273	ENSMUSG00000030744
UniProt	P23396	P62908
RefSeq (mRNA)	NM_001260507 NM_001005 NM_001256802 NM_001260506	NM_012052
RefSeq (protein)	NP_000996 NP_001243731 NP_001247435 NP_001247436	NP_036182
Yerleşim (UCSC)	Krom. 11: 75.4 – 75.42 Mb	n/a
PubMed araması	[2]	[3]
Vikiveri
İnsan'ı Gör/Düzenle Fare'yi Gör/Düzenle

40S ribozomal protein S3, insanların 11. kromozomunda yer alan RPS3 geni tarafından kodlanan bir proteindir.^[4][5][6]

Kaynakça

1. ^ GRCh38: Ensembl release 89: ENSG00000149273 - Ensembl, May 2017
2. "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
3. "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
4. Pogue-Geile K, Geiser JR, Shu M, Miller C, Wool IG, Meisler AI, Pipas JM (Aug 1991). "Ribosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal protein". Mol. Cell. Biol. 11 (8). ss. 3842-9. doi:10.1128/MCB.11.8.3842. PMC 361167 $2. PMID 1712897. 
5. Polakiewicz RD, Munroe DJ, Sait SN, Tycowski KT, Nowak NJ, Shows TB, Housman DE, Page DC (Jul 1995). "Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3-q13.5". Genomics. 25 (2). ss. 577-80. doi:10.1016/0888-7543(95)80063-R . PMID 7789996. 
6. "Entrez Gene: RPS3 ribosomal protein S3". 2 Kasım 2008 tarihinde kaynağından arşivlendi. 

Ek okuma

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• Zhang XT, Tan YM, Tan YH (1990). "Isolation of a cDNA encoding human 40S ribosomal protein s3". Nucleic Acids Res. 18 (22). s. 6689. doi:10.1093/nar/18.22.6689. PMC 332635 $2. PMID 2129557. 
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• Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N (2002). "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes". Genome Res. 12 (3). ss. 379-90. doi:10.1101/gr.214202. PMC 155282 $2. PMID 11875025. 
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• Lim Y, Lee SM, Kim M, Lee JY, Moon EP, Lee BJ, Kim J (2002). "Complete genomic structure of human rpS3: identification of functional U15b snoRNA in the fifth intron". Gene. 286 (2). ss. 291-7. doi:10.1016/S0378-1119(02)00502-4. PMID 11943484. 
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