CD24 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
CD24[d][1] |
Молекуляр функция |
protein tyrosine kinase activator activity[d][2], signal transducer activity[d][3], связывание с белками плазмы[d][4][5][6][…] һәм protein kinase binding[d][4] |
Күзәнәк компоненты |
мембрана[d][7][8], күзәнәк мембранасы[d][7], күзәнәк өслеге[d][9], anchored component of external side of plasma membrane[d][10], липидный рафт[d][2], anchored component of membrane[d][7] һәм внутренний компонент клетки[d][11] |
Биологик процесс |
response to hypoxia[d][12], regulation of MAPK cascade[d][2], positive regulation of MAP kinase activity[d][13], regulation of cytokine-mediated signaling pathway[d][14], positive regulation of cytosolic calcium ion concentration[d][15][16], chemokine receptor transport out of membrane raft[d][7], T cell costimulation[d][17], regulation of phosphorylation[d][2], сигнальный путь Wnt[d][9], negative regulation of transforming growth factor beta3 production[d][18], cell activation[d][15], immune response-regulating cell surface receptor signaling pathway[d][2], response to estrogen[d][8], respiratory burst[d][15], intrinsic apoptotic signaling pathway[d][2], glomerular parietal epithelial cell differentiation[d][19], агрегация клеток[d][7], glomerular visceral epithelial cell differentiation[d][19], cholesterol homeostasis[d][14], regulation of epithelial cell differentiation[d][18], response to molecule of bacterial origin[d][20], миграция клеток[d][14], B cell receptor transport into membrane raft[d][2], positive regulation of nephron tubule epithelial cell differentiation[d][21], positive regulation of activated T cell proliferation[d][17], positive regulation of protein tyrosine kinase activity[d][7] һәм cell-cell adhesion[d][6] |
CD24 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[22][23]
- ↑ 1,0 1,1 UniProt
- ↑ 2,0 2,1 2,2 2,3 2,4 2,5 2,6 T Suzuki, N Kiyokawa, T Taguchi et al. CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system // J. Immunol. — Baltimore: 2001. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.166.9.5567 — PMID:11313396
- ↑ D Figarella-Branger, H Moreau, Pellissier J. F. et al. CD24, a signal-transducing molecule expressed on human B lymphocytes, is a marker for human regenerating muscle // Acta Neuropathol. (Berl) — Springer Science+Business Media, 1993. — ISSN 0001-6322; 1432-0533 — doi:10.1007/BF00304142 — PMID:8213086
- ↑ 4,0 4,1 Zarn J. A., Zimmermann S. M., Pass M. K. et al. Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase lyn in an erythroleukemia cell line // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 1996. — ISSN 0006-291X; 1090-2104 — doi:10.1006/BBRC.1996.1184 — PMID:8753773
- ↑ S Aigner, Sthoeger Z. M., M Fogel et al. CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cells // Blood — American Society of Hematology, Elsevier BV, 1997. — ISSN 0006-4971; 1528-0020 — PMID:9129046
- ↑ 6,0 6,1 Chen C., He Z., Sai P. et al. Inhibition of human CD24 binding to platelet-bound P-selectin by monoclonal antibody // Proceedings of the Western Pharmacology Society — 2004. — ISSN 0083-8969 — PMID:15633604
- ↑ 7,0 7,1 7,2 7,3 7,4 7,5 GOA
- ↑ 8,0 8,1 Brown P. O., Ross D. T. Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes // Nucleic Acids Res. — OUP, University of Oxford, 1999. — ISSN 0305-1048; 1362-4962; 1362-4954 — doi:10.1093/NAR/27.6.1517 — PMID:10037815
- ↑ 9,0 9,1 M Shulewitz, I Soloviev, T Wu et al. Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer // Oncogene — NPG, 2006. — ISSN 0950-9232; 1476-5594 — doi:10.1038/SJ.ONC.1209470 — PMID:16532032
- ↑ Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ GOA
- ↑ Elia G., Neri D. Modulation of gene expression by hypoxia in human umbilical cord vein endothelial cells: A transcriptomic and proteomic study // Proteomics / L. Stimson — Wiley, 2004. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200300689 — PMID:15174142
- ↑ Taguchi T., Kiyokawa N., Mimori K. et al. Pre-B cell antigen receptor-mediated signal inhibits CD24-induced apoptosis in human pre-B cells // J. Immunol. — Baltimore: 2003. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.170.1.252 — PMID:12496407
- ↑ 14,0 14,1 14,2 Altevogt P. CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells // J. Cell Sci. — The Company of Biologists, 2006. — ISSN 0021-9533; 1477-9137 — doi:10.1242/JCS.02741 — PMID:16390867
- ↑ 15,0 15,1 15,2 Lund-Johansen F., Olweus J Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens // Eur. J. Immunol. — Wiley-Blackwell, 1993. — ISSN 0014-2980; 1521-4141 — doi:10.1002/EJI.1830231110 — PMID:8223854
- ↑ GF F., Majdic O, Gadd S et al. Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules // J. Immunol. — Baltimore: 1990. — ISSN 0022-1767; 1550-6606 — PMID:2153173
- ↑ 17,0 17,1 Salamone M. C., C Rosselot, Salamone G. V. et al. Antibodies recognizing CD24 LAP epitope on human T cells enhance CD28 and IL-2 T cell proliferation // J. Leukoc. Biol. / L. Montaner — Wiley-Blackwell, 2001. — ISSN 0741-5400; 1938-3673 — PMID:11272271
- ↑ 18,0 18,1 P Ye, Nadkarni M. A., N Hunter Regulation of E-cadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 2006. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2006.08.033 — PMID:16930538
- ↑ 19,0 19,1 Angelotti M. L., Lazzeri E., Mazzinghi B. et al. Regeneration of glomerular podocytes by human renal progenitors // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008070709 — PMID:19092120
- ↑ Gekara N. O., S Weiss Lipid rafts clustering and signalling by listeriolysin O // Biochem. Soc. Trans. — Portland Press, 2004. — ISSN 0300-5127; 1470-8752 — doi:10.1042/BST0320712 — PMID:15493995
- ↑ Annunziato F. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2006. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2006010089 — PMID:16885410
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)