CD27 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
CD27[d][1] |
Молекуляр функция |
tumor necrosis factor-activated receptor activity[d][2], cysteine-type endopeptidase inhibitor activity involved in apoptotic process[d][3], связывание с белками плазмы[d][3][4][5][…], transmembrane signaling receptor activity[d][6][7], связывание с белками плазмы[d][3][4][8][…] һәм cysteine-type endopeptidase inhibitor activity involved in apoptotic process[d][3][9] |
Күзәнәк компоненты |
күзәнәк тышындагы өлкә[d][10], мембрана өлеше[d][7], күзәнәк мембранасы өлеше[d][11][2], мембрана[d][7][7], күзәнәк өслеге[d][7], күзәнәк мембранасы[d][7], наружная сторона клеточной мембраны[d][2], күзәнәк мембранасы өлеше[d][3] һәм наружная сторона клеточной мембраны[d][7][9] |
Биологик процесс |
негативная регуляция апоптоза[d][7][7][3], response to lipopolysaccharide[d][2], response to ethanol[d][7], negative regulation of T cell apoptotic process[d][7], extrinsic apoptotic signaling pathway[d][4], regulation of cell population proliferation[d][2], cell surface receptor signaling pathway[d][6], апоптоз[d][7], tumor necrosis factor-mediated signaling pathway[d][7], immunoglobulin mediated immune response[d][6], positive regulation of JNK cascade[d][7][7], воспалительная реакция[d][2], иммун җавап[d][2], negative regulation of cysteine-type endopeptidase activity involved in apoptotic process[d][7], positive regulation of B cell differentiation[d][12][7], positive regulation of T cell differentiation[d][7], multicellular organism development[d][2], positive regulation of NIK/NF-kappaB signaling[d][3], response to ethanol[d][7][9], positive regulation of JNK cascade[d][7][7][9], negative regulation of T cell apoptotic process[d][7][9], extrinsic apoptotic signaling pathway[d][4][9] һәм негативная регуляция апоптоза[d][7][7][3][…] |
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CD27 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[13][14]
- ↑ 1,0 1,1 UniProt
- ↑ 2,0 2,1 2,2 2,3 2,4 2,5 2,6 2,7 GOA
- ↑ 3,0 3,1 3,2 3,3 3,4 3,5 3,6 3,7 Hase H., Kanno Y., Kojima H. et al. CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2002. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M209050200 — PMID:12324477
- ↑ 4,0 4,1 4,2 4,3 Prasad K. V., Z Ao, Y Yoon et al. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1997. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.94.12.6346 — PMID:9177220
- ↑ Henke A. The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22 // Mol. Cell. Biochem. — Springer Science+Business Media, 2006. — ISSN 0300-8177; 1573-4919; 0013-9424 — doi:10.1007/S11010-005-9082-6 — PMID:16683188
- ↑ 6,0 6,1 6,2 Hirano T., Yonekubo I., Shimo K. et al. CD27 synergizes with CD40 to induce IgM, IgG, and IgA antibody responses of peripheral blood B cells in the presence of IL-2 and IL-10 // Immunology Letters — Elsevier BV, 2003. — ISSN 0165-2478; 1879-0542 — doi:10.1016/S0165-2478(03)00156-1 — PMID:14556986
- ↑ 7,00 7,01 7,02 7,03 7,04 7,05 7,06 7,07 7,08 7,09 7,10 7,11 7,12 7,13 7,14 7,15 7,16 7,17 7,18 7,19 7,20 7,21 7,22 7,23 GOA
- ↑ Barabási A., Taipale M., Weile J. et al. Widespread macromolecular interaction perturbations in human genetic disorders // Cell — Cell Press, Elsevier BV, 2015. — ISSN 0092-8674; 1097-4172 — doi:10.1016/J.CELL.2015.04.013 — PMID:25910212
- ↑ 9,0 9,1 9,2 9,3 9,4 9,5 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ T Nakatsuji High levels of serum soluble CD27 correlated with renal dysfunction // Clin. Exp. Med. — Springer Science+Business Media, 2003. — ISSN 1591-8890; 1591-9528 — doi:10.1007/S102380300006 — PMID:12624711
- ↑ Hase H., Kanno Y., Kojima H. et al. CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2002. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M209050200 — PMID:12324477
- ↑ K Agematsu Memory B cells and CD27 // Histology & Histopathology — University of Murcia, 2000. — ISSN 0213-3911; 1699-5848 — doi:10.14670/HH-15.573 — PMID:10809378
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)