ERCC2 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
ERCC2[d][1] |
Молекуляр функция |
ДНК-связывающий[d][2][2], 4 iron, 4 sulfur cluster binding[d][2], protein kinase activity[d][3], ATP-dependent activity, acting on DNA[d][4][3], нуклеотид-связывающий[d][2], helicase activity[d][2][2], protein N-terminus binding[d][5], iron-sulfur cluster binding[d][2], DNA helicase activity[d][6], связывание с ионом металла[d][2], hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides[d][2], protein C-terminus binding[d][7], связывание с белками плазмы[d][8][5][9][…], nucleic acid binding[d][2], RNA polymerase II CTD heptapeptide repeat kinase activity[d][10], 5'-3' DNA helicase activity[d][9][4], гидролазная активность[d][2], АТФ-связанные[d][2][2], damaged DNA binding[d][11], DNA helicase activity[d][2][11], RNA polymerase II CTD heptapeptide repeat kinase activity[d][3][11], protein-macromolecule adaptor activity[d][9] һәм 5'-3' DNA helicase activity[d][11] |
Күзәнәк компоненты |
цитоплазма[2][8][12], cyclin-dependent protein kinase activating kinase holoenzyme complex[d][13][14], веретено деления[d][2][12], transcription factor TFIIH holo complex[d][15][3], transcription factor TFIIH core complex[d][2], цитоскелет[d][2], төш[6][6][6][…], MMXD complex[d][12], нуклеоплазма[d][2][2], transcription factor TFIID complex[d][16], цитозоль[d][2], төш[2][2][2][…] һәм CAK-ERCC2 complex[d][17][9] |
Биологик процесс |
termination of RNA polymerase I transcription[d][2], regulation of mitotic cell cycle phase transition[d][18], bone mineralization[d][2], hair cycle process[d][2], response to hypoxia[d][2], ДНК-зависимая регуляция транскрипции[d][6], embryonic cleavage[d][2], hair follicle maturation[d][2], multicellular organism growth[d][2], chromosome segregation[d][12][2], transcription initiation from RNA polymerase I promoter[d][2], transcription elongation from RNA polymerase II promoter[d][2], hair cell differentiation[d][19][2], старение человека[d][2], extracellular matrix organization[d][2], in utero embryonic development[d][2], 7-methylguanosine mRNA capping[d][2], transcription by RNA polymerase II[d][20][6][10], post-embryonic development[d][2], response to oxidative stress[d][21][6], транскрипция, ДНК-зависимая[d][6], cellular response to DNA damage stimulus[d][2], ДНК-зависимая позитивная регуляция транскрипции[d][14], global genome nucleotide-excision repair[d][2], hematopoietic stem cell differentiation[d][2], арка мие үсеше[d][2], УФ-защита[d][22][2], positive regulation of DNA binding[d][2], central nervous system myelin formation[d][2], transcription-coupled nucleotide-excision repair[d][2][4], transcription initiation from RNA polymerase II promoter[d][2], пролиферация[d][2], nucleotide-excision repair, DNA incision[d][6][23], nucleobase-containing compound metabolic process[d][2], response to UV[d][6], положительная регуляция транскрипции РНК полимеразой II промотор[d][24], развитие кожи[d][2], erythrocyte maturation[d][2], апоптоз[d][25], Эксцизионная репарация нуклеотидов[d][26][22][2][…], nucleotide-excision repair, preincision complex stabilization[d][2], репарация ДНК[d][2][2], вирусный процесс[d][2], фосфорилация белка[d][2], nucleotide-excision repair, preincision complex assembly[d][2], nucleotide-excision repair, DNA incision, 5'-to lesion[d][2], развитие эмбрионического органа[d][2], DNA duplex unwinding[d][6], regulation of mitotic recombination[d][11], nucleotide-excision repair, DNA duplex unwinding[d][27], transcription by RNA polymerase II[d][4][2][3][…], response to oxidative stress[d][28][2][11], response to UV[d][2][11], nucleotide-excision repair, DNA incision[d][2][24][11], ДНК-зависимая позитивная регуляция транскрипции[d][17][11], positive regulation of mitotic recombination[d][11], nucleotide-excision repair, DNA duplex unwinding[d][2][11], nucleotide-excision repair, DNA incision, 3'-to lesion[d][2] һәм transcription elongation from RNA polymerase I promoter[d][2] |
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