FGF18 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
FGF18[d][1] |
Молекуляр функция |
fibroblast growth factor receptor binding[d][2], type 1 fibroblast growth factor receptor binding[d][3], type 2 fibroblast growth factor receptor binding[d][3], growth factor activity[d][4][2][2], protein tyrosine kinase activity[d][5], phosphatidylinositol-4,5-bisphosphate 3-kinase activity[d][5] һәм 1-phosphatidylinositol-3-kinase activity[d][5] |
Күзәнәк компоненты |
күзәнәк тышындагы өлкә[d][2][2][2], ядрышко[d][2] һәм күзәнәк тышындагы мохит[d][4] |
Биологик процесс |
intramembranous ossification[d][2], positive regulation of vascular endothelial growth factor receptor signaling pathway[d][2], regulation of sprouting angiogenesis[d][6], positive regulation of endothelial cell chemotaxis to fibroblast growth factor[d][6], positive regulation of MAP kinase activity[d][6], оссификация[d][2], үпкәләр үсеше[d][2], передача сигнала между клетками[d][4], морфогенез анатомической структуры[d][4], chondrocyte development[d][2], endochondral ossification[d][2], MAPK cascade[d][2], fibroblast growth factor receptor signaling pathway[d][2][2][2], positive regulation of chondrocyte differentiation[d][2], Ангиогенез[d][2], позитивная регуляция пролиферации клеток[d][4][2], regulation of endothelial cell proliferation[d][6], передача сигнала[d][4], phosphatidylinositol phosphate biosynthetic process[d][5], peptidyl-tyrosine phosphorylation[d][5], phosphatidylinositol-3-phosphate biosynthetic process[d][5], regulation of signaling receptor activity[d][2], позитивная регуляция сигналов от протеинкиназы В[d][2], positive regulation of blood vessel endothelial cell migration[d][7], positive regulation of angiogenesis[d][7] һәм positive regulation of ERK1 and ERK2 cascade[d][2] |
FGF18 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[8][9]
- ↑ 1,0 1,1 UniProt
- ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 2,21 2,22 GOA
- ↑ 3,0 3,1 Mohammadi M., Olsen S. K., Linhardt R. J. Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain // Genes Dev. — Cold Spring Harbor Laboratory Press, 2005. — ISSN 0890-9369; 1549-5477 — doi:10.1101/GAD.1365406 — PMID:16384934
- ↑ 4,0 4,1 4,2 4,3 4,4 4,5 Hu M. C., Qiu W. R., Wang Y. P. et al. FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation // Mol. Cell. Biol. — ASM, 1998. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.18.10.6063 — PMID:9742123
- ↑ 5,0 5,1 5,2 5,3 5,4 5,5 GOA
- ↑ 6,0 6,1 6,2 6,3 M Antoine, W Wirz, Tag C. G. et al. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 2006. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2006.05.105 — PMID:16756958
- ↑ 7,0 7,1 Yang Q., Jia C., Wang P. et al. MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation // Int. J. Cardiol. / Andrew Justin Stewart Coats — Elsevier BV, 2014. — ISSN 0167-5273; 1874-1754 — doi:10.1016/J.IJCARD.2014.09.204 — PMID:25449503
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)