HEPH |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
Гефестин[d][1] |
Молекуляр функция |
oxidoreductase activity[d][2][2], ferrous iron binding[d][3], copper ion binding[d][3][2], связывание с ионом металла[d][2], ferroxidase activity[d][4], oxidoreductase activity, acting on metal ions[d][5], ferroxidase activity[d][3][6] һәм oxidoreductase activity[d][2][2][6] |
Күзәнәк компоненты |
perinuclear region of cytoplasm[d][2], мембрана өлеше[d][2], күзәнәк мембранасы[d][7][7][7], basolateral plasma membrane[d][8], внутренний компонент клетки[d][9], мембрана[d][2], күзәнәк тышындагы мохит[d][5] һәм күзәнәк мембранасы[d][2][2][2][…] |
Биологик процесс |
copper ion transport[d][2], iron ion homeostasis[d][7], iron ion transport[d][4][7], ion transport[d][2], cellular iron ion homeostasis[d][2][2], cellular iron ion homeostasis[d][7], iron ion transport[d][3][2][6] һәм iron ion homeostasis[d][2][6] |
HEPH (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[10][11]
- ↑ 1,0 1,1 UniProt
- ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 GOA
- ↑ 3,0 3,1 3,2 3,3 Vashchenko G. M. Functional role of the putative iron ligands in the ferroxidase activity of recombinant human hephaestin // Journal of Biological Inorganic Chemistry — Springer Science+Business Media, 2012. — ISSN 0949-8257; 1432-1327 — doi:10.1007/S00775-012-0932-X — PMID:22961397
- ↑ 4,0 4,1 Vashchenko G. M. Functional role of the putative iron ligands in the ferroxidase activity of recombinant human hephaestin // Journal of Biological Inorganic Chemistry — Springer Science+Business Media, 2012. — ISSN 0949-8257; 1432-1327 — doi:10.1007/S00775-012-0932-X — PMID:22961397
- ↑ 5,0 5,1 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ 6,0 6,1 6,2 6,3 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ 7,0 7,1 7,2 7,3 7,4 7,5 GOA
- ↑ Buchan A. Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells // American Journal of Physiology: Gastrointestinal and Liver Physiology — American Physiological Society, 2009. — ISSN 0193-1857; 1522-1547 — doi:10.1152/AJPGI.00453.2009 — PMID:20019163
- ↑ Buchan A. Human hephaestin expression is not limited to enterocytes of the gastrointestinal tract but is also found in the antrum, the enteric nervous system, and pancreatic {beta}-cells // American Journal of Physiology: Gastrointestinal and Liver Physiology — American Physiological Society, 2009. — ISSN 0193-1857; 1522-1547 — doi:10.1152/AJPGI.00453.2009 — PMID:20019163
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)