OSM (ген)

OSM
Сурәт
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген OSM[d][1]
Молекуляр функция cytokine activity[d][2][3][3][…], oncostatin-M receptor binding[d][4][5], growth factor activity[d][6], cytokine activity[d][7][8][8][…] һәм oncostatin-M receptor binding[d][9][6][8]
Күзәнәк компоненты күзәнәк тышындагы өлкә[d][8][8][8] һәм күзәнәк тышындагы мохит[d][7][8]
Биологик процесс oncostatin-M-mediated signaling pathway[d][5], positive regulation of peptidyl-serine phosphorylation[d][10], развитие многоклеточного организма[d][11], иммун җавап[d][8], позитивная регуляция пролиферации клеток[d][6], positive regulation of acute inflammatory response[d][6], regulation of growth[d][8], пролиферация[d][12], negative regulation of hormone secretion[d][13], positive regulation of cell division[d][8], positive regulation of MAPK cascade[d][10], негативная регуляция пролиферации клеток[d][11], положительная регуляция транскрипции РНК полимеразой II промотор[d][10], positive regulation of tyrosine phosphorylation of STAT protein[d][14], regulation of signaling receptor activity[d][8], positive regulation of peptidyl-tyrosine phosphorylation[d][10][6], cytokine-mediated signaling pathway[d][8], positive regulation of phosphatidylinositol 3-kinase signaling[d][15], positive regulation of inflammatory response[d][15], позитивная регуляция сигналов от протеинкиназы В[d][15], oncostatin-M-mediated signaling pathway[d][8][6] һәм regulation of hematopoietic stem cell differentiation[d][12]

OSM (ген) (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[16][17]

Искәрмәләр

[үзгәртү | вики-текстны үзгәртү]
  1. ↑ 1,0 1,1 UniProt
  2. ↑ N Malik, Kallestad J. C., Gunderson N. L. et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M // Mol. Cell. Biol. — ASM, 1989. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.9.7.2847 — PMID:2779549
  3. ↑ 3,0 3,1 GOA
  4. ↑ Tanaka M, Hara T, NG C. et al. Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit // Blood — American Society of Hematology, Elsevier BV, 1999. — 12 p. — ISSN 0006-4971; 1528-0020 — PMID:9920829
  5. ↑ 5,0 5,1 B Mosley, Imus C. D., D Friend et al. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.271.51.32635 — PMID:8999038
  6. ↑ 6,0 6,1 6,2 6,3 6,4 6,5 B Mosley, Imus C. D., D Friend et al. Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.271.51.32635 — PMID:8999038
  7. ↑ 7,0 7,1 N Malik, Kallestad J. C., Gunderson N. L. et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M // Mol. Cell. Biol. — ASM, 1989. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.9.7.2847 — PMID:2779549
  8. ↑ 8,00 8,01 8,02 8,03 8,04 8,05 8,06 8,07 8,08 8,09 8,10 8,11 8,12 GOA
  9. ↑ Tanaka M, Hara T, NG C. et al. Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit // Blood — American Society of Hematology, Elsevier BV, 1999. — 12 p. — ISSN 0006-4971; 1528-0020 — PMID:9920829
  10. ↑ 10,0 10,1 10,2 10,3 Yin T, YC Y. Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1994. — ISSN 0021-9258; 1083-351X; 1067-8816 — PMID:7508917
  11. ↑ 11,0 11,1 Rose T. M., Bruce A. G. Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6 // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 1991. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.88.19.8641 — PMID:1717982
  12. ↑ 12,0 12,1 Miles S. A., O. Martínez-Maza, A. Rezai et al. Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells // Science / H. Thorp — Northern America: AAAS, 1992. — ISSN 0036-8075; 1095-9203 — doi:10.1126/SCIENCE.1542793 — PMID:1542793
  13. ↑ M Yamaguchi, N Miki, M Ono et al. Inhibition of growth hormone-releasing factor production in mouse placenta by cytokines using gp130 as a signal transducer // Endocrinology / T. K. Woodruff — Los Angeles, Calif: Endocrine Society, OUP, 1995. — ISSN 0013-7227; 1945-7170 — doi:10.1210/ENDO.136.3.7867561 — PMID:7867561
  14. ↑ Maminishkis A. CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium // PLOS ONE / PLOS ONE Editors — PLoS, 2011. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0023148 — PMID:21912637
  15. ↑ 15,0 15,1 15,2 Kijlstra A. MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease // Br. J. Ophthalmol. — BMJ, 2017. — ISSN 0007-1161; 1468-2079 — doi:10.1136/BJOPHTHALMOL-2017-311079 — PMID:28972028
  16. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  17. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

[үзгәртү | вики-текстны үзгәртү]
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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