POMT1 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
POMT1[d][1] |
Молекуляр функция |
glycosyltransferase activity[d][2], dolichyl-phosphate-mannose-protein mannosyltransferase activity[d][2][3], трансферазная активность[d][2], mannosyltransferase activity[d][4][5], связывание с ионом металла[d][2], dolichyl-phosphate-mannose-protein mannosyltransferase activity[d][2] һәм mannosyltransferase activity[d][6][7][2] |
Күзәнәк компоненты |
мембрана өлеше[d][6][2], Акросома[d][2], эндоплазматик челтәр[6][2], Саркоплазматический ретикулум[d][2], мембрана[d][2][2], endoplasmic reticulum membrane[d][2][2][8] һәм endoplasmic reticulum membrane[d][2][2][8][…] |
Биологик процесс |
развитие многоклеточного организма[d][6], protein glycosylation[d][2], protein O-linked glycosylation[d][2][6][2], extracellular matrix organization[d][2], protein O-linked mannosylation[d][5], ER-associated misfolded protein catabolic process[d][5], mannosylation[d][5], positive regulation of protein O-linked glycosylation[d][2], Углеводный обмен[d][6], protein O-linked mannosylation[d][7] һәм protein O-linked mannosylation[d][7][3] |
POMT1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[9][10]
- ↑ 1,0 1,1 UniProt
- ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 GOA
- ↑ 3,0 3,1 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ Jurado L. A., A Coloma, J Cruces Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1 // Genomics / A. Engel — Academic Press, Elsevier BV, 1999. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1999.5819 — PMID:10366449
- ↑ 5,0 5,1 5,2 5,3 GOA
- ↑ 6,0 6,1 6,2 6,3 6,4 6,5 Jurado L. A., A Coloma, J Cruces Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1 // Genomics / A. Engel — Academic Press, Elsevier BV, 1999. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1999.5819 — PMID:10366449
- ↑ 7,0 7,1 7,2 Narimatsu Y., Joshi H. J., Yang Z. et al. Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2017. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M117.794487 — PMID:28512129
- ↑ 8,0 8,1 Manya H., Chiba A., Yoshida A. et al. Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2004. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0307228101 — PMID:14699049
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)