TCIRG1 |
Нинди таксонда бар |
H. sapiens[d][1] |
Кодлаучы ген |
TCIRG1[d][1] |
Молекуляр функция |
transporter activity[d][2], ATPase binding[d][3], proton-transporting ATPase activity, rotational mechanism[d][3] һәм proton transmembrane transporter activity[d][4] |
Күзәнәк компоненты |
мембрана өлеше[d][4], proton-transporting V-type ATPase, V0 domain[d][4], phagocytic vesicle membrane[d][5], мембрана[d][4], vacuolar proton-transporting V-type ATPase, V0 domain[d][4], күзәнәк мембранасы[d][5][6][5], күзәнәк мембранасы өлеше[d][7], lysosomal membrane[d][8], apical plasma membrane[d][9], митохондрия[5], vacuolar proton-transporting V-type ATPase complex[d][3], endosome membrane[d][4], ficolin-1-rich granule membrane[d][4], lysosomal membrane[d][10], күзәнәк мембранасы[d][4][11][4][…], төш[4], лизосома[4], late endosome[d][4], secretory granule membrane[d][4], phagocytic vesicle membrane[d][4][4] һәм phagocytic vesicle[d][4] |
Биологик процесс |
protein catabolic process in the vacuole[d][4][4], insulin receptor signaling pathway[d][4], transferrin transport[d][4], vacuolar proton-transporting V-type ATPase complex assembly[d][5], ion transport[d][4], vacuolar acidification[d][3], cellular defense response[d][11], ion transmembrane transport[d][4], позитивная регуляция пролиферации клеток[d][11], ATP synthesis coupled proton transport[d][5], macroautophagy[d][4][4], phagosome acidification[d][5], neutrophil degranulation[d][4], перенос[d][5], proton transmembrane transport[d][2], оссификация[d][4], osteoclast proliferation[d][4], immunoglobulin production[d][4], cellular calcium ion homeostasis[d][4], апоптоз[d][4], воспалительная реакция[d][4], regulation of proton transport[d][4], response to silver ion[d][4], Регуляция экспрессии генов[d][4], immunoglobulin mediated immune response[d][4], optic nerve development[d][4], myeloid cell differentiation[d][4], B cell differentiation[d][4], T cell differentiation[d][4], osteoclast differentiation[d][4], memory T cell activation[d][4], T-helper 1 cell activation[d][4], odontogenesis[d][4], T cell homeostasis[d][4], tooth eruption[d][4], костная резорбция[d][4], regulation of osteoblast differentiation[d][4], pH reduction[d][4], homeostasis of number of cells[d][4], regulation of insulin secretion[d][4], retina development in camera-type eye[d][4], hematopoietic stem cell homeostasis[d][4], enamel mineralization[d][4], cellular response to cytokine stimulus[d][4], phagosome acidification[d][4][4] һәм dentin mineralization[d][4] |
TCIRG1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[12][13]
- ↑ 1,0 1,1 UniProt
- ↑ 2,0 2,1 Li Y. P., W Chen, P Stashenko Molecular cloning and characterization of a putative novel human osteoclast-specific 116-kDa vacuolar proton pump subunit // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 1996. — ISSN 0006-291X; 1090-2104 — doi:10.1006/BBRC.1996.0145 — PMID:8579597
- ↑ 3,0 3,1 3,2 3,3 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 4,12 4,13 4,14 4,15 4,16 4,17 4,18 4,19 4,20 4,21 4,22 4,23 4,24 4,25 4,26 4,27 4,28 4,29 4,30 4,31 4,32 4,33 4,34 4,35 4,36 4,37 4,38 4,39 4,40 4,41 4,42 4,43 4,44 4,45 4,46 4,47 4,48 4,49 4,50 4,51 4,52 4,53 4,54 4,55 4,56 GOA
- ↑ 5,0 5,1 5,2 5,3 5,4 5,5 5,6 5,7 GOA
- ↑ N Utku, T Heinemann, Tullius S. G. et al. Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein // Immunity — Cell Press, Elsevier BV, 1998. — ISSN 1074-7613; 1097-4180 — doi:10.1016/S1074-7613(00)80634-2 — PMID:9806637
- ↑ T Heinemann, Bulwin G. C., J Randall et al. Genomic organization of the gene coding for TIRC7, a novel membrane protein essential for T cell activation // Genomics / A. Engel — Academic Press, Elsevier BV, 1999. — ISSN 0888-7543; 1089-8646 — doi:10.1006/GENO.1999.5751 — PMID:10329006
- ↑ Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // Traffic — Wiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854 — doi:10.1111/J.1600-0854.2007.00643.X — PMID:17897319
- ↑ Devuyst O., Karet F. E., Villa A. et al. Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2005. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2004090761 — PMID:15800125
- ↑ Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // Traffic — Wiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854 — doi:10.1111/J.1600-0854.2007.00643.X — PMID:17897319
- ↑ 11,0 11,1 11,2 N Utku, T Heinemann, Tullius S. G. et al. Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein // Immunity — Cell Press, Elsevier BV, 1998. — ISSN 1074-7613; 1097-4180 — doi:10.1016/S1074-7613(00)80634-2 — PMID:9806637
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)