16-亚甲基-6-脱氢-17α-羟孕酮

16-亚甲基-6-脱氢-17α-羟孕酮
臨床資料
其他名稱Deacetylsuperlutin; 16-Methylene-6-dehydro-17α-hydroxyprogesterone; 16-Methylenepregna-4,6-diene-3,20-dione; 16-Methyl-4,6,16-pregnatriene-3,20-dione
藥物類別Progestogen; Progestin
识别信息
  • (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-16-methylidene-2,8,9,11,12,14,15,17-octahydro-1H-cyclopenta[a]phenanthren-3-one
CAS号6723-96-2
PubChem CID
化学信息
化学式C22H28O2
摩尔质量324.46 g·mol−1
3D模型（JSmol（英语：JSmol））
  • CC(=O)[C@H]1C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=CC4=CC(=O)CC[C@]34C)C
  • InChI=1S/C22H28O2/c1-13-11-19-17-6-5-15-12-16(24)7-9-21(15,3)18(17)8-10-22(19,4)20(13)14(2)23/h5-6,12,17-20H,1,7-11H2,2-4H3/t17-,18+,19+,20-,21+,22+/m1/s1
  • Key:SLRUDSFURBMIQT-HQZKGGBDSA-N

16-亚甲基-6-脱氢-17α-羟孕酮（英語：16-methylene-6-dehydro-17α-hydroxyprogesterone 或 Methenmadinone、deacetylsuperlutin）是一种人工合成的甾体有机化合物，化学式C22H28O2，用作孕激素類药物，从未上市销售。[1][2][3]

參考文獻

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  1. ^ G.W.A Milne. Ashgate Handbook of Endocrine Agents and Steroids. Taylor & Francis. 1 November 2017: 158–. ISBN 978-1-351-74347-1. 
  2. ^ George W.A Milne. Drugs: Synonyms and Properties: Synonyms and Properties. Taylor & Francis. 8 May 2018: 1572–. ISBN 978-1-351-78989-9. 
  3. ^ Shapiro EL, Weber L, Harris H, Miskowicz C, Neri R, Herzog HL. Synthesis and biological activity of 17-esters of 6-dehydro-16-methylene-17 -hydroxyprogesterones. J. Med. Chem. July 1972, 15 (7): 716–20. PMID 5043870. doi:10.1021/jm00277a006. 

外部連結

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