60S核糖体亚基

60S亞基（英語：Eukaryotic large ribosomal subunit (60S)）是真核80S核糖體的大亞基，「60S」是核糖體顆粒根據其沉降係數以斯維德伯格單位來表示及命名的，它在結構和功能上與70S原核核糖體的50S亞基有關。[1][2][3][4][5][6]但是，60S亞基比原核50S亞基大得多，並且包含其他多個蛋白質片段及核糖體RNA擴展片段。

參見

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參考資料

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  1. ^ 醫學主題詞表（MeSH）：60S+Ribosome+Subunits
  2. ^ Klinge, S; Voigts-Hoffmann, F; Leibundgut, M; Arpagaus, S; Ban, N. Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6. Science. 2011, 334 (6058): 941–948. PMID 22052974. doi:10.1126/science.1211204. 
  3. ^ Ben-Shem, A; Garreau; de Loubresse, N; Melnikov, S; Jenner, L; Yusupova, G; Yusupov, M. The structure of the eukaryotic ribosome at 3.0 Å resolution. Science. Dec 2011, 334 (6062): 1524–1529. PMID 22096102. doi:10.1126/science.1212642. 
  4. ^ Ban, N; Nissen, P; Hansen, J; Moore, PB; Steitz, TA. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science. Aug 2000, 289 (5481): 905–920. PMID 10937989. doi:10.1126/science.289.5481.905. 
  5. ^ Cate, JH; Yusupov, MM; Yusupova, GZ; Earnest, TN; Noller, HF. X-ray crystal structures of 70S ribosome functional complexes. Science. Sep 1999, 285 (5436): 2095–2104. PMID 10497122. doi:10.1126/science.285.5436.2095. 
  6. ^ Yusupov, MM; Yusupova, GZ; Baucom, A; Lieberman, K; Earnest, TN; Cate, JH; Noller, HF. Crystal structure of the ribosome at 5.5 A resolution. Science. May 2001, 292 (5518): 883–896. PMID 11283358. doi:10.1126/science.1060089. 

外部連結

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