RNA聚合酶V

RNA聚合酶V（英語：RNA polymerase V）是一种植物细胞核中特有的RNA聚合酶，和RNA聚合酶IV一样参与小干扰RNA(siRNA)的转录。RNA聚合酶V转录siRNA诱导DNA甲基化而导致异染色质沉默。[1]

RNA聚合酶V由12个亚基组成，与RNA聚合酶Ⅱ亚基旁系同源。两个最大的亚基（催化位置）是最保守的，与真核生物和细菌的聚合酶都有很高的相似性。[2]

参考文献

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  1. ^ Wierzbicki, A; Haag, J; Pikaard, CS. Noncoding transcription by RNA Polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes. Cell. 2008, 135: 635–648. PMC 2602798 可免费查阅. PMID 19013275. doi:10.1016/j.cell.2008.09.035. 
  2. ^ Ream, TS; Haag, JR; Wierzbicki, AT; Nicora, CD; Norbeck, AD; Zhu, JK; Hagen, G; Guilfoyle, TJ; Pasa-Tolić, L; Pikaard, CS. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Mol Cell: 192–203. PMC 2946823 可免费查阅. PMID 19110459. doi:10.1016/j.molcel.2008.12.015.