GPR27

GPR27
Identifiers
Aliases	GPR27, SREB1, G protein-coupled receptor 27
External IDs	OMIM: 605187; MGI: 1202299; GeneCards: GPR27
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p13 Start 71,753,855 bp[1] End 71,756,496 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 D3 Start 99,669,640 bp[2] End 99,672,027 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus endothelial cell superior vestibular nucleus Brodmann area 23 subthalamic nucleus inferior ganglion of vagus nerve nucleus accumbens spinal cord caudate nucleus C1 segment Top expressed in olfactory tubercle nucleus accumbens anterior amygdaloid area fossa substantia nigra ventromedial nucleus lateral septal nucleus vas deferens Region I of hippocampus proper subiculum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway signal transduction G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 2850 14761 Ensembl ENSG00000170837 ENSMUSG00000072875 UniProt Q9NS67 O54897 RefSeq (mRNA) NM_018971 NM_008158 RefSeq (protein) NP_061844 NP_032184 Location (UCSC) Chr 3: 71.75 – 71.76 Mb Chr 6: 99.67 – 99.67 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 27 is a protein that in humans is encoded by the GPR27 gene.^[5][6]

See also

• SREB

References

1. GRCh38: Ensembl release 89: ENSG00000170837 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000072875 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
6. "Entrez Gene: GPR27 G protein-coupled receptor 27".