Skin care

Skin care or skincare is the practice and process of maintaining and improving the health and appearance of the skin. It includes washing, moisturizing, protecting from the sun, and treating skin problems like acne and dryness.^[1] Facial care is skin care for the face.

Skin care is at the interface of cosmetics and dermatology.^[2] Skin care differs from dermatology by its inclusion of non-physician professionals, such as estheticians and nursing staff. Skin care includes modifications of individual behavior and of environmental and working conditions.^[3] Skin care is applied during recovery from wound healing, radiation therapy, and the management of some medications.

Skin care needs vary according to age, diseases, wounds, exposure to the sun, environmental extremes, and chemicals. Skin care products exist as regulated prescription drugs and as topical agents marketed as cosmetics but having no clinical proof of efficacy. A skin care physician is called a dermatologist.

General care

The skin is the largest organ in the human body, protecting against pathogens, irritants, ultraviolet light, and mechanical injury, while also regulating temperature and water release as perspiration.^[4] Simple habits like washing and applying lotion may provide benefit, but little is known scientifically about the clinical efficacy of these practices. Skin care routines, even in hospitals and medical facilities, may be based on personal beliefs, preferences, and local circumstances rather than current evidence or best practices.^[5]

Lifestyle and diet

Drinking enough water may help to keep skin hydrated, especially in individuals who are chronically dehydrated.^[6] A poor diet lacking vitamins can lead to skin problems, such as scurvy, pellagra, and numerous subclinical skin pathologies that have not been studied in detail.^[7] Lack of sleep has been shown to make conditions like atopic dermatitis, eczema and psoriasis worse, and these conditions have in turn been shown to reduce sleep quality.^[8]

Products

There are many different forms of skin care treatments, each offering unique benefits for the skin. Some popular forms of facial care include a variety of different types of facials,^[9] facial massage,^[10] and the use of masks.^[11] These treatments can help to cleanse, hydrate, and rejuvenate the skin, leaving it looking and feeling refreshed. To achieve the best results, choose products that are suitable for your specific skin type and that address any particular skin concerns you may have. The effectiveness of skin care depends on various factors such as skin type,^[12] sensitivity,^[13] age,^[14] hyperpigmentation,^[15] and acne.^[16] The labels on cleansing and skin care products can be confusing because they use unclear words like "mild" or "gentle". This makes it hard to know how well a product works or what it actually does. Just because a product has a certain ingredient doesn't mean it is effective—how well it works depends on the whole formula and how it is used. People often mix up what a product does (like moisturizing) with what an ingredient does (like glycerin keeping moisture in or petrolatum protecting the skin).^[5]

In Europe, cosmetics are regulated under a law named Safer cosmetics for people in the EU, which enforces strict safety requirements, simplifies application and compliance procedures for companies and regulatory authorities, ensures that cosmetics products can be marketed, maintains rules governing new technical and scientific developments, and bans animal testing.^[17]

In the U.S., the Federal Food, Drug, and Cosmetic Act groups skin care products into two main categories: cosmetics and drugs. While prescription drugs must go through a strict approval process before they can be sold, cosmetics do not need FDA approval before being sold, although they are still monitored for labeling, safety, and are regulated.^[18]^[2]

Cosmeceutical and nutricosmetic are marketing terms with no scientific evidence pertaining to skin care or health, and no acceptance for validity as skin care products under US law.^[19]

Professional care

Dermatologists and estheticians offer professional skin care services. Consulting with a dermatologist is recommended for persistent or severe skin conditions. They can prescribe medications and customized skin care treatments. Some example procedures include chemical peels, laser resurfacing, photorejuvenation, photodynamic therapy, dermabrasion and microdermabrasion, collagen induction therapy, injectable fillers, botox injection,^[20] retinol therapy, ultrasonic skin treatment, and hair removal.^[21]

Routine

Skin care interventions consist of applying one or more products to specific areas of the skin in a specific order. A skin care routine may consist of cleansing, exfoliation, toning, targeted treatment, and moisturizing. Instructions for how much to use, how often, and for how long are not always clear.^[5]

Cleansing

Cleansing is the process of removing dirt, oil, makeup, and other impurities from the skin.^[22] Lathering cleansers, a common type of facial cleanser, generate lather when used, thanks to a surfactant level greater than the CMC (critical micelle concentration). These cleansers contain surfactants with short hydrophobic chains, enabling faster and higher levels of lather.^[23] Most lathering cleansers on the market use synthetic surfactants designed to be mild to the skin, reducing skin damage compared to naturally derived surfactants. However, they may be less effective at removing oil-soluble makeup. Liquid lathering cleansers clean through the chemical process of emulsification, suspending or emulsifying dirt and oils, thus allowing them to be removed from the skin during the rinse process. Exfoliating cleansers are used to cleanse and exfoliate the skin twice per day, in the morning and evening.^[24] There also exist soapless or "no-rinse" cleansers (syndets).^[5]

Exfoliating

Exfoliation is a skincare process that involves the removal of dead skin cells from the skin's surface, promoting skin renewal and cell turnover and rejuvenation.^[25] Chemical exfoliating (such as glycolic acid and salicylic acid), causes controlled destruction of the epidermis, leading to subsequent rejuvenation of the skin. Chemical peels are a form of targeted skin exfoliation, with different depths of peels inducing varying degrees of outer layer removal of the skin. Superficial peels, for example, reduce epidermal melanin and are used in the treatment of post-inflammatory hyperpigmentation (PIH). Additionally, exfoliation can be achieved through physical scrubbing using additives such as oats or coffee grounds.^[26] Over-exfoliation can lead to irritation and barrier damage, which can be avoided by careful routine design and product choice such as micro-dosed acid formulations.^[27]

Toning

Toners help balance the skin's pH and are typically used after cleansing but prior to moisturizing. They can have a number of benefits, depending on their formula and should be chosen to suit an individuals skin needs, such as reducing pores (using toners that have salicylic acid) for oily and acne skin types, brightening complexion (with toners that have vitamin C), soothing inflammation (via toners with ingredients such as aloe vera) for sensitive skin types or using toners that include retinol for aging skin, which can help to improve fine lines.^[28]^[29]

Moisturizing

Moisturizers are used to hydrate dry skin, improve and prevent rough, cracked skin, restore the natural feel of the skin to make it soft, silky, and smooth, or alleviate skin conditions such as eczema, contact dermatitis, or rosacea. In essence, most people use moisturizers to ensure their skin feels and looks nice without any discomfort.^[30] It is a crucial aspect of skincare, particularly for areas prone to dryness or that have impaired barrier function.^[31] Moisturizing skincare can contribute to preventing and treating skin diseases and disorders.^[32] The term "moisturization" holds different meanings depending on its intended purpose and how it is applied. Different formulations exist for different skin types, such as lightweight gels for oily skin and rich creams for dry skin.

Targeted treatment

Specialized products such as serums, facial masks, and eye cream contain active ingredients to address specific skin concerns.

Skin care by age

Neonate

Guidelines for neonatal skin care have been developed. Nevertheless, the pediatric and dermatological communities have not reached a consensus on best cleansing practices, as good quality scientific evidence is scarce.^[33] Immersion in water seems superior to washing alone, and use of synthetic detergents or mild liquid baby cleansers seems comparable or superior to water alone.^[33]

Children and adolescents

Dermatologists normally recommend that children wash their skin with a mild cleanser, use moisturizing lotion as needed, and wear sunscreen every day. Elaborate skin care routines are promoted on social media platforms such as TikTok. This has led to children and teens using harsh and inappropriate products, such as anti-aging products, which provide no benefit to young skin and may be harmful. It has also encouraged children and teens to wear sunscreen every day.^[34]

Elderly

Skin ageing is associated with increased skin vulnerability,^[35] and the texture and colour of the skin can change over time. Although wrinkles occur naturally due to ageing, smoking can intensify the appearance of wrinkles. Sunspots, dryness, wrinkles, and melanomas can occur from UV exposure over time, whether it be through the sun or through tanning beds. Exposure to UV can make skin less elastic. Skin problems including pruritus are common in the elderly but are often inadequately addressed.^[36] A literature review of studies assessing the maintenance of skin integrity in the elderly found most studies to have low levels of evidence, but the review concluded that skin-cleansing with synthetic detergents or amphoteric surfactants induced less skin dryness than using soap and water.^[35] Moisturizers with humectants helped with skin dryness and skin barrier occlusive reduced skin injuries.^[35] When taking baths or showers, using warm water rather than hot water can aid with dryness.

There is limited evidence that moisturizing soap bar; combinations of water soak, oil soak, and lotion are effective in maintaining the skin integrity of elderly people when compared to standard care.^[37]

Specific skin concerns

Sun protection

Sunscreen is a skincare product designed to protect the skin from the harmful effects of chronic exposure to UV radiation. Though the sun is beneficial in order for the human body to get its daily dose of vitamin D, unprotected excessive sunlight can cause extreme damage to the skin. Ultraviolet (UVA and UVB) radiation in the sun's rays can cause sunburn in varying degrees, early ageing and an increased risk of skin cancer.^[38] UV exposure can cause patches of uneven skin tone and dry out the skin. It can reduce skin's elasticity and encourage sagging and wrinkle formation. UV radiation can lead to skin thickening, wrinkle formation, inflammation, and even carcinogenesis. These effects occur due to the continuous oxidative stress state induced by an excessive generation of reactive oxygen species (ROS) from UV irradiation. This oxidative stress ultimately leads to cell apoptosis events and degradation of collagen,^[39] resulting in the undesired morphologic changes in the skin.

Sunscreen helps prevent these harmful effects by providing a protective barrier against UV radiation, reducing the risk of skin damage and associated skin conditions.^[40] Sunscreen is generally recommended to be applied before sun exposure and reapplied regularly, especially after sweating or swimming. Sunscreen should be applied to all areas of the skin that will be exposed to sunlight, and at least a tablespoon (25 ml) should be applied to each limb, the face, chest, and back, to ensure thorough coverage. Many tinted moisturizers, foundations and primers now contain some form of SPF.

Sunscreens may come in the form of creams, gels or lotions; their SPF number indicates their effectiveness in protecting the skin from the sun's radiation. There are sunscreens available to suit every skin type; in particular, those with oily skin should choose non-comedogenic sunscreens; those with dry skins should choose sunscreens with moisturizers to help keep skin hydrated, and those with sensitive skin should choose unscented, hypoallergenic sunscreen and spot-test in an inconspicuous place (such as the inside of the elbow or behind the ear) to ensure that it does not irritate the skin.

Skin sensitivity and irritation

Applying moisturizer twice a day may strengthen the skin's natural barrier, but how well it works depends on the formulation of the moisturizer. Even on healthy skin, moisturizers can help protect against things that might cause irritation. 2.5% or 5% dexpanthenol is known to reduce irritation.^[5] Products made for sensitive skin are usually labeled as gentle, fragrance-free, and hypoallergenic.

Oily skin

Healthy sebaceous glands produce a substance called sebum, a naturally healthy skin lubricant.^[41]^[42] When the skin produces excessive sebum, it becomes heavy and thick in texture, known as oily skin.^[42] Oily skin is typified by shininess, blemishes and pimples.^[41] The oily-skin type is not necessarily bad, since such skin is less prone to wrinkling, or other signs of ageing,^[41] because the oil helps to keep needed moisture locked into the epidermis (outermost layer of skin). The negative aspect of the oily-skin type is that oily complexions are especially susceptible to clogged pores, blackheads, and buildup of dead skin cells on the surface of the skin.^[41] Oily skin can be sallow and rough in texture and tends to have large, clearly visible pores everywhere, except around the eyes and neck.^[41] A high glycemic-index diet and dairy products (except for cheese) consumption increase IGF-1 generation, which in turn increases sebum production.^[42] Overwashing the skin does not cause sebum overproduction but may cause dryness; it is possible to have skin that is both dry and oily.^[42]

Dry skin

Dry skin does not have enough moisture. It will show signs like flaking, tightness, roughness, redness, or cracks. If the skin is very dry, it might also look swollen or extra soft. Common areas that get dry include the face, scalp, and back—especially when exposed to air or clothing. However, places where the skin folds, like under the arms, between the toes, and around the groin, usually do not get as dry.^[5]

Washing dry skin should be done daily using lukewarm water (less than 37 °C (99 °F)). Avoid long or frequent baths and showers. Try to keep bath time under five minutes per day. If the skin is extremely dry, avoid using regular soap and water, as they can make dryness worse. Instead, use gentle, alkali-free cleansers with a pH of 4 to 5, especially ones with ingredients like urea, lactic acid, or glycerin, which help keep moisture in.^[5]

Moisturizing dry skin at least twice a day is important. If the skin is very dry, moisturizing more often may help. Thicker, oil-based creams work best for very dry skin. Aqueous cream should be avoided. It also helps to apply a skin protectant. Using a moisturizer with niacinamide and glycerin twice a day has been shown to strengthen the skin and reduce dryness, versus moisturizers without niacinamide.^[5]

Diaper rash

To keep the skin healthy, it's best to clean it gently every day with a no-rinse cleanser (pH 5.5). Using soap and water takes more time and does not work as well. After cleaning, the skin should be dried gently—don't scrub, as this can damage the skin's natural barrier. A protective cream or ointment, such as zinc oxide, petroleum jelly, or dimethicone, should be applied to shield the skin. Cleaning should be done after every accident to limit contact with urine or stool.^[5]

Acne

Acne is defined by clogged pores and bacteria. According to the American Academy of Dermatology, between 40 and 50 million Americans develop acne each year.^[43] Although many associate acne with adolescence, acne can occur at any age, with its causes including heredity, hormones, menstruation, food, and emotional stress.^[43]

Acne is treated with ingredients like salicylic acid, benzoyl peroxide, and retinoids. Those with inflammatory acne should exfoliate with caution as the procedure may make conditions worse and consult a dermatologist before treatment.^[43] Benzoyl peroxide is a drying agent and is typically found in concentrations of 2.5 - 10%.^[44]

Eczema and dermatitis

Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash.^[45] Dermatitis may also be called eczema, but the same term is often used for the most common type of skin inflammation, atopic dermatitis.^[46] Dermatitis can be managed with moisturizers and prescription anti-inflammatory treatments, whereas topical antimicrobials, antiseptics, and antihistamines are not recommended by dermatologists.^[47]

Psoriasis

Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin.^[48] Topical skin care agents are typically used for mild disease.

Rosacea

Rosacea is a long-term skin condition that typically causes redness, visible blood vessels, and small bumps on the face.^[49] Medications with good evidence include topical metronidazole,^[50] ivermectin and azelaic acid.^[51]

Hyperpigmentation

Hyperpigmentation, also known as dark spots, is the darkening of an area of skin or nails caused by increased melanin. Many topical treatments disrupt the synthesis of melanin by inhibiting the enzyme tyrosine hydroxylase.

Aging and wrinkles

Anti-aging creams are predominantly moisturizer-based skin care products marketed with unproven claims of making the consumer look younger by reducing, masking or preventing signs of skin aging such as wrinkles.^[53] In the United States, anti-aging products are commonly marketed with false health claims, and are deemed to be among various scams on consumers.^[54]^[55]

Pressure ulcer

Pressure sores, also called bedsores or pressure ulcers, are injuries to the skin and tissue caused by staying in one position for too long. To treat them, the skin should be washed with lukewarm water and dried completely, especially in areas where skin touches skin, like between the toes, under the breasts, in the groin, and under the arms. Harsh soaps should be avoided—it is better to use gentle, pH-balanced cleansers. Moisturizers can help protect the skin, but they shouldn't be used between the toes. It is best to apply a hypoallergenic moisturizer twice a day, especially on the arms and legs, and avoid rubbing the skin too hard.^[5]

Wound healing

Wound healing is a complex and fragile process in which the skin repairs itself after injury. It is susceptible to interruption or failure that creates non-healing chronic wounds.^[56]

Radiation

Radiation induces skin reactions in the treated area, particularly in the axilla, head and neck, perineum and skin fold regions.^[57] Formulations with moisturising, anti-inflammatory, anti-microbial and wound healing properties are often used, but no preferred approach or individual product has been identified as best practice.^[57]^[58] Soft silicone dressings that act as barriers to friction may be helpful.^[57] In breast cancer, calendula cream may reduce the severity of radiation effects on the dark spot corrector.^[58]^[59] Deodorant use after completing radiation treatment has been controversial but is now recommended for practice.^[59]

EGFR side effects

Epidermal growth factor receptor (EGFR) inhibitors are medications used in cancer treatment. These medications commonly cause skin and nail problems, including rashes, dry skin and paronychia.^[60] Preventive intensive moisturizing with emollient ointments several times, avoidance of water-based creams and water soaks (although in certain circumstances white vinegar or potassium permanganate soaks may help), protection the skin from excessive exposure to sunshine, and soap substitutes which are less dehydrating for the skin than normal soaps, as well as shampoos that reduce the risk of scalp folliculitis, are recommended. Treatment measures with topical antibiotic medication can be helpful.^[60]^[61]^[62]

References

^ "Do You Really Need a Skin Care Routine?". Northwestern Medicine. December 2021. Retrieved 1 December 2025.
^ ^a ^b Kessler R (8 September 2015). "More than Cosmetic Changes: Taking Stock of Personal Care Product Safety". Environmental Health Perspectives. 123 (5). Bibcode:2015EnvHP.123.A120K. doi:10.1289/ehp.123-A120. PMC 4421754.
^ Schwanitz HJ, Riehl U, Schlesinger T, et al. (2003). "Skin care management: educational aspects". Int Arch Occup Environ Health. 76 (5): 374–81. Bibcode:2003IAOEH..76..374S. doi:10.1007/s00420-002-0428-z. PMID 12719982. S2CID 41740856.
^ Yousef H, Alhajj M, Fakoya AO, Sharma S (8 June 2024). "Anatomy, Skin (Integument), Epidermis". StatPearls, US National Library of Medicine. PMID 29262154. Retrieved 11 February 2026.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Lichterfeld A, Hauss A, Surber C, Peters T, Blume-Peytavi U, Kottner J (2015). "Evidence-Based Skin Care: A Systematic Literature Review and the Development of a Basic Skin Care Algorithm" (PDF). J Wound Ostomy Continence Nurs. 42 (5): 501–24. doi:10.1097/WON.0000000000000162. PMID 26165590. S2CID 3841975. Archived (PDF) from the original on 30 April 2023. Retrieved 13 December 2019.
^ Akdeniz, M.; Tomova-Simitchieva, T.; Dobos, G.; Blume-Peytavi, U.; Kottner, J. (August 2018). "Does dietary fluid intake affect skin hydration in healthy humans? A systematic literature review". Skin Research and Technology. 24 (3): 459–465. doi:10.1111/srt.12454. PMID 29392767.
^ Lee, Benjamin Y.; Hogan, Daniel J.; Ursine, Susonne; Yanamandra, Krishne; Bocchini, Joseph A. (May 2006). "Personal observation of skin disorders in malnutrition". Clinics in Dermatology. 24 (3): 222–227. doi:10.1016/j.clindermatol.2005.11.002. PMID 16714203.
^ Mann, Caroline; Gorai, Surajit; Staubach-Renz, Petra; Goldust, Mohamad (June 2023). "Sleep disorders in dermatology – a comprehensive review". Journal der Deutschen Dermatologischen Gesellschaft. 21 (6): 577–584. doi:10.1111/ddg.14992. PMID 37235517.
^ "8 Popular Types of Facials and Their Benefits". L'Oréal Paris. Retrieved 1 December 2025.
^ Okuda, Itsuko; Takeda, Mizuho; Taira, Masahiro; Kobayashi, Toyoaki; Inomata, Ken; Yoshioka, Naoki (May 2022). "Objective analysis of the effectiveness of facial massage using breakthrough computed tomographic technology: A preliminary pilot study". Skin Research and Technology. 28 (3): 472–479. doi:10.1111/srt.13152. ISSN 1600-0846. PMC 9907650. PMID 35416349.
^ Matthews, Sarah (19 September 2025). "The best LED face masks, tested: eight light therapy devices that are worth the hype". The Guardian. ISSN 0261-3077. Retrieved 1 December 2025.
^ "What Is My Skin Type? 5 Types Explained". NIVEA. Retrieved 1 December 2025.
^ "The best moisturisers for sensitive skin, starting from just £5". Good Housekeeping. 24 September 2025. Retrieved 1 December 2025.
^ McCarty, Grace (25 November 2025). "The Best Skin Care Routine for Mature Skin, According to Dermatologists". Glamour. Retrieved 1 December 2025.
^ "A comprehensive guide to the best hyperpigmentation treatments". Harper's BAZAAR. 11 March 2025. Retrieved 1 December 2025.
^ "10 skin care habits that can worsen acne". American Academy of Dermatology Association. Retrieved 1 December 2025.
^ "Safer cosmetics for people in the EU". EUR-Lex, European Union Law. 11 July 2013. Retrieved 11 February 2026.
^ "Federal Food, Drug, and Cosmetic Act of 1938, as amended". US Food and Drug Administration. 25 February 2022. Retrieved 11 February 2026.
^ "Cosmeceutical". US Food and Drug Administration. 25 February 2022. Retrieved 11 February 2026.
^ "BOTOX® Cosmetic (onabotulinumtoxinA)" (PDF).
^ Penzer R, Ersser S. Principles of Skin Care: A Guide for Nurses and Health Care Practitioners. John Wiley & Sons, 2010. ISBN 9781405170871 [1]
^ "The 8 Best Facial Cleansers". The New York Times. 14 October 2025. ISSN 0362-4331. Retrieved 1 December 2025.
^ Zhou, Yawen; Wang, Shan; Lv, Mengdie; Niu, Jinping; Xu, Baocai (2017). "Analysis of the Effects of Hydrocarbon Chain on Foam Properties of Alkyl Polyglycosides". Journal of Surfactants and Detergents. 20 (3): 623–630. doi:10.1007/s11743-017-1955-7. ISSN 1558-9293.
^ Iman Balagam (3 November 2025). "The Best Exfoliating Face Washes Keep Skin Clean, Soft, and Smooth". Vogue. Retrieved 1 December 2025.
^ Marta I. Rendon; Diane S. Berson; Joel L. Cohen (2010). "Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing". The Journal of Clinical and Aesthetic Dermatology. 3 (7): 32–43. ISSN 2689-9175. PMC 2921757. PMID 20725555.
^ "How to safely exfoliate at home". American Academy of Dermatology Association. Retrieved 1 December 2025.
^ Das, Anupam; Sen, Dyotona; Jadhwar, Sameer (26 November 2025). "Dermatologists' perspectives on daily gentle exfoliation for sensitive and oily/acne-prone skin: Insights from a national survey". Cosmoderma. 5 124. doi:10.25259/CSDM_164_2025.
^ "This 'Forgotten' Skincare Step Can Improve Acne, Dark Spots, And Wrinkles". Women's Health. 16 May 2025. Retrieved 2 December 2025.
^ "The Benefits of Using Facial Toner". Lookfantastic. 25 September 2020. Retrieved 2 December 2025.
^ "Moisturizers: Do they work?". Harvard Health. 1 February 2008. Retrieved 1 December 2025.
^ Harwood, Anne; Nassereddin, Ali; Krishnamurthy, Karthik (2025), "Moisturizers", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31424755, retrieved 1 December 2025
^ "Skin Diseases: Types of, Symptoms, Treatment & Prevention". Cleveland Clinic. Archived from the original on 24 February 2026. Retrieved 1 December 2025.
^ ^a ^b Blume-Peytavi U, Hauser M, Stamatas GN, Pathirana D, Garcia Bartels N (2012). "Skin care practices for newborns and infants: review of the clinical evidence for best practices". Pediatr Dermatol. 29 (1): 1–14. doi:10.1111/j.1525-1470.2011.01594.x. PMID 22011065. S2CID 27763545.
^ Gecker, Jocelyn (31 August 2024). "Which skin care products should young girls use? Dermatologists recommend this simple routine". AP News. Retrieved 6 September 2024.
^ ^a ^b ^c Kottner J, Lichterfeld A, Blume-Peytavi U (2013). "Maintaining skin integrity in the aged: a systematic review". Br. J. Dermatol. 169 (3): 528–42. doi:10.1111/bjd.12469. hdl:1854/LU-8691723. PMID 23773110. S2CID 42191236.
^ Beauregard S, Gilchrest BA (1987). "A survey of skin problems and skin care regimens in the elderly". Arch Dermatol. 123 (12): 1638–43. doi:10.1001/archderm.1987.01660360066014. PMID 3688904.
^ Cowdell, Fiona; Jadotte, Yuri T; Ersser, Steven J; Danby, Simon; Lawton, Sandra; Roberts, Amanda; Dyson, Judith (23 January 2020). Cochrane Skin Group (ed.). "Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings". Cochrane Database of Systematic Reviews. 1 (1) CD011377. doi:10.1002/14651858.CD011377.pub2. PMC 6996088. PMID 32006460.
^ Clark A, Hessler JL (August 2015). "Skin Care". Facial Plast Surg Clin North Am. 23 (3): 285–95. doi:10.1016/j.fsc.2015.04.002. PMID 26208767. S2CID 32542642.
^ Paculová, Vendula; Prasad, Ankush; Pospíšil, Pavel (19 August 2025). "Oxidative Fragmentation of Collagen in Skin: Relevance to Skin Aging and Skin Diseases". Journal of Investigative Dermatology. 146 (2): 550–554.e2. doi:10.1016/j.jid.2025.08.005. ISSN 0022-202X. PMID 40840842.
^ Kumar, Sonal (29 May 2024). "What are the short-term and long-term effects of sun exposure?". Bupa. Retrieved 1 December 2025.
^ ^a ^b ^c ^d ^e "Skin care" (analysis), Health-Cares.net, 2007, webpage: HCcare Archived 12 December 2007 at the Wayback Machine
^ ^a ^b ^c ^d Sakuma TH, Maibach HI (2012). "Oily skin: an overview". Skin Pharmacology and Physiology. 25 (5): 227–235. doi:10.1159/000338978. PMID 22722766. S2CID 2446947.
^ ^a ^b ^c "Acne clinical guideline". American Academy of Dermatology. 2018. Archived from the original on 18 May 2019. Retrieved 26 September 2019.
^ "Topical Acne Drug Products". CFR - Code of Federal Regulations, Title 21, U.S. Food and Drug Administration. 1 April 2018. Archived from the original on 23 December 2016. Retrieved 23 December 2016.
^ Nedorost ST (2012). Generalized Dermatitis in Clinical Practice. Springer Science & Business Media. pp. 1–3, 9, 13–14. ISBN 978-1-4471-2897-7. Archived from the original on 15 August 2016. Retrieved 29 July 2016.
^ Johansson SG, Bieber T, Dahl R, et al. (May 2004). "Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003". The Journal of Allergy and Clinical Immunology. 113 (5): 832–836. Bibcode:2004JACI..113..832J. doi:10.1016/j.jaci.2003.12.591. PMID 15131563.
^ Sidbury R, Alikhan A, Bercovitch L, et al. (July 2023). "Guidelines of care for the management of atopic dermatitis in adults with topical therapies". Journal of the American Academy of Dermatology. 89 (1): e1–e20. doi:10.1016/j.jaad.2022.12.029. PMID 36641009.
^ Boehncke WH, Schön MP (September 2015). "Psoriasis". Lancet. 386 (9997): 983–94. Bibcode:2015Lanc..386..983B. doi:10.1016/S0140-6736(14)61909-7. PMID 26025581. S2CID 208793879.
^ "Questions and Answers about Rosacea". www.niams.nih.gov. April 2016. Archived from the original on 13 May 2017. Retrieved 5 June 2017.
^ Desai SR, Baldwin H, Del Rosso JQ, Gallo RL, Bhatia N, Harper JC, York JP, Gold LS (February 2024). "Microencapsulated Benzoyl Peroxide for Rosacea in Context: A Review of the Current Treatment Landscape". Drugs. 84 (3): 275–284. doi:10.1007/s40265-024-02003-w. PMC 10982091. PMID 38418773.
^ van Zuuren, EJ; Fedorowicz, Z; Carter, B; van der Linden, MM; Charland, L (28 April 2015). "Interventions for rosacea". The Cochrane Database of Systematic Reviews. 4 (4) CD003262. doi:10.1002/14651858.CD003262.pub5. PMC 6481562. PMID 25919144.
^ "Warning Letters Address Drug Claims Made for Products Marketed as Cosmetics". US Food and Drug Administration. 1 April 2022. Archived from the original on 5 September 2019. Retrieved 1 June 2023. products are not generally recognized as safe and effective for the above-referenced uses and, therefore, these products are "new drugs" under section 201(p) of the Act [21 U.S.C. § 321(p)]. New drugs may not be legally introduced or delivered for introduction into interstate commerce without prior approval from FDA.
^ Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC (July 2012). "Skin anti-aging strategies". Dermato-Endocrinology. 4 (3): 308–19. doi:10.4161/derm.22804. PMC 3583892. PMID 23467476.
^ "Common health scams". Federal Trade Commission, Office of the Inspector General, US Government. 1 January 2022. Retrieved 31 May 2023. Despite claims about pills and treatments leading to the fountain of youth, there's nothing you can buy that has been proven to slow or reverse the aging process. And many companies selling these lotions, creams, and supplements don't have sufficient scientific evidence to show they work.
^ "Are Some Cosmetics Promising Too Much?". US Food and Drug Administration. 23 March 2015. Archived from the original on 12 September 2019. Retrieved 1 June 2023. products are being marketed with drug claims—indicating that they are intended to treat or prevent disease, or change the body's structure or functions. The agency tells companies that they need to remove any drug claims from their products' labeling or seek FDA approval to market these products as drugs.
^ Flanagan M. Wound Healing and Skin Integrity: Principles and Practice. John Wiley & Sons, 2013. ISBN 9780470659779
^ ^a ^b ^c Herst PM (2014). "Protecting the radiation-damaged skin from friction: a mini review". J Med Radiat Sci. 61 (2): 119–25. doi:10.1002/jmrs.46. PMC 4175840. PMID 26229646.
^ ^a ^b McQuestion M (2006). "Evidence-based skin care management in radiation therapy". Semin Oncol Nurs. 22 (3): 163–73. doi:10.1016/j.soncn.2006.04.004. PMID 16893745.
^ ^a ^b McQuestion M (2011). "Evidence-based skin care management in radiation therapy: clinical update". Semin Oncol Nurs. 27 (2): e1–17. doi:10.1016/j.soncn.2011.02.009. PMID 21514477.
^ ^a ^b Califano R, Tariq N, Compton S, et al. (2015). "Expert Consensus on the Management of Adverse Events from EGFR Tyrosine Kinase Inhibitors in the UK". Drugs. 75 (12): 1335–48. doi:10.1007/s40265-015-0434-6. PMC 4532717. PMID 26187773.
^ Thatcher N, Nicolson M, Groves RW, et al. (2009). "Expert consensus on the management of erlotinib-associated cutaneous toxicity in the U.K." Oncologist. 14 (8): 840–7. doi:10.1634/theoncologist.2009-0055. PMID 19679688. S2CID 2455128.
^ Kiyohara Y, Yamazaki N, Kishi A (2013). "Erlotinib-related skin toxicities: treatment strategies in patients with metastatic non-small cell lung cancer". J. Am. Acad. Dermatol. 69 (3): 463–72. doi:10.1016/j.jaad.2013.02.025. PMID 23602600.

Authority control databases
International	GND
National	United States Czech Republic Latvia Israel
Other	Yale LUX