OPN1SW

edit

Opsin 1 (pigment kupe)
Identifikatori
Simboli	OPN1SW; BCP; BOP; CBT
Vanjski ID	OMIM: 190900 MGI: 99438 HomoloGene: 1291 GeneCards: OPN1SW Gene
Ontologija gena Molekularna funkcija • aktivnost rodopsinu-sličnog receptora • receptorska aktivnost • aktivnost fotorecptora plave svetlosti Celularna komponenta • fotoreceptorski spoljašnje segment • integralno sa ćelijskom membranom • membrana Biološki proces • prenos signala • signalni put G-protein spregnutog receptora • vizuelna percepcija • fototransdukcija • protein-hromofor veza • respons na stimulus
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta	Čovek	Miš
Entrez	611	12057
Ensembl	ENSG00000128617	ENSMUSG00000058831
UniProt	P03999	P51491
RefSeq (mRNA)	NM_001708	NM_007538
RefSeq (protein)	NP_001699	NP_031564
Lokacija (UCSC)	Chr 7: 128.2 - 128.2 Mb	Chr 6: 29.33 - 29.33 Mb
PubMed pretraga	[1]	[2]

OPN1SW, plavo-senzitivni opsin je protein koji je kod ljudi kodiran OPN1SW genom.^[1][2][3]

Povezano

• Opsin

Literatura

1. Nathans J, Thomas D, Hogness DS (Apr 1986). „Molecular genetics of human color vision: the genes encoding blue, green, and red pigments”. Science 232 (4747): 193–202. DOI:10.1126/science.2937147. PMID 2937147. 
2. Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). „Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32”. Hum Genet 93 (1): 79–80. PMID 8270261. 
3. „Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)”. 

Dodatna literatura

• Applebury ML, Hargrave PA (1987). „Molecular biology of the visual pigments.”. Vision Res. 26 (12): 1881–95. DOI:10.1016/0042-6989(86)90115-X. PMID 3303660. 
• Swanson WH, Cohen JM (2003). „Color vision.”. Ophthalmology clinics of North America 16 (2): 179–203. DOI:10.1016/S0896-1549(03)00004-X. PMID 12809157. 
• Weitz CJ, Went LN, Nathans J (1992). „Human tritanopia associated with a third amino acid substitution in the blue-sensitive visual pigment.”. Am. J. Hum. Genet. 51 (2): 444–6. PMC 1682686. PMID 1386496. 
• Weitz CJ, Miyake Y, Shinzato K, et al. (1992). „Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin.”. Am. J. Hum. Genet. 50 (3): 498–507. PMC 1684278. PMID 1531728. 
• Oprian DD, Asenjo AB, Lee N, Pelletier SL (1992). „Design, chemical synthesis, and expression of genes for the three human color vision pigments.”. Biochemistry 30 (48): 11367–72. DOI:10.1021/bi00112a002. PMID 1742276. 
• Sarkar G, Sommer SS (1989). „Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity.”. Science 244 (4902): 331–4. DOI:10.1126/science.2565599. PMID 2565599. 
• Nathans J, Piantanida TP, Eddy RL, et al. (1986). „Molecular genetics of inherited variation in human color vision.”. Science 232 (4747): 203–10. DOI:10.1126/science.3485310. PMID 3485310. 
• Shimmin LC, Mai P, Li WH (1997). „Sequences and evolution of human and squirrel monkey blue opsin genes.”. J. Mol. Evol. 44 (4): 378–82. DOI:10.1007/PL00006157. PMID 9089077. 
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). „Human chromosome 7: DNA sequence and biology.”. Science 300 (5620): 767–72. DOI:10.1126/science.1083423. PMC 2882961. PMID 12690205. 
• Gunther KL, Neitz J, Neitz M (2006). „A novel mutation in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect.”. Vis. Neurosci. 23 (3-4): 403–9. DOI:10.1017/S0952523806233169. PMID 16961973.