RRH

Retinalni pigment epitelnog homologa rodopsina
Retinalni pigment epitelnog homologa rodopsina
Identifikatori
Simboli	RRH;
Vanjski ID	OMIM: 605224 MGI: 1097709 HomoloGene: 55977 GeneCards: RRH Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora; • receptorska aktivnost;
Celularna komponenta	• integralno sa ćelijskom membranom; • membrana;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptora; • vizuelna percepcija; • protein-hromofor veza;
Pregled RNK izražavanja
	podaci
Ortolozi
Vrsta	Čovek
Entrez	10692
Ensembl	ENSG00000180245
UniProt	O14718
RefSeq (mRNA)	NM_006583
RefSeq (protein)	NP_006574
Lokacija (UCSC)	Chr 4:; 110.97 - 110.99 Mb
PubMed pretraga	[1]

RRH, ili peropsin, vizuelnom pigmentu-sličan receptor, je protein koji je kod čoveka kcodiran RRH genom.^[1]^[2] Opsini su ćlanovi familije G protein-spregnutih receptora. Ovaj gen pripada sedam-eksonskog familiji sisarskih opsinskih gena, koja obuhvata opsin 5 i retinalni G protein spregnuti receptor.^[3]

Literatura

^ Sun H, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (1997). „Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium”. Proc Natl Acad Sci U S A. 94 (18): 9893—8. PMC 23288 . PMID 9275222. doi:10.1073/pnas.94.18.9893.
^ Kalsi G; Kuo PH; Aliev F; et al. (2010). „A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts”. Human Molecular Genetics. 19 (12): 2497—506. PMID 20332099. doi:10.1093/hmg/ddq112. Приступљено 1. 4. 2011.
^ Rivolta C, Berson EL, Dryja TP (2006). „Mutation screening of the peropsin gene, a retinal pigment epithelium specific rhodopsin homolog, in patients with retinitis pigmentosa and allied diseases”. Molecular Vision. 12: 1511—5. PMID 17167409. Приступљено 1. 4. 2011.

Dodatna literatura

Bellingham J, Wells DJ, Foster RG (2003). „In silico characterisation and chromosomal localisation of human RRH (peropsin)--implications for opsin evolution.”. BMC Genomics. 4: 3. PMC 149353 . PMID 12542842. doi:10.1186/1471-2164-4-3.

[pmid9275222-1] Sun H, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (1997). „Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium”. Proc Natl Acad Sci U S A. 94 (18): 9893—8. PMC 23288 . PMID 9275222. doi:10.1073/pnas.94.18.9893.

[pmid20332099-2] Kalsi G; Kuo PH; Aliev F; et al. (2010). „A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts”. Human Molecular Genetics. 19 (12): 2497—506. PMID 20332099. doi:10.1093/hmg/ddq112. Приступљено 1. 4. 2011.

[pmid17167409-3] Rivolta C, Berson EL, Dryja TP (2006). „Mutation screening of the peropsin gene, a retinal pigment epithelium specific rhodopsin homolog, in patients with retinitis pigmentosa and allied diseases”. Molecular Vision. 12: 1511—5. PMID 17167409. Приступљено 1. 4. 2011.

[1]

[2]

[3]