SIB-1553A

{{Chembox-lat | ImageFile = SIB-1553A.svg | ImageSize = 200px | ImageAlt = | IUPACName = (R/S)-4-{[2-(1-Metil-2-pirolidinil)etil]tio}fenol hidrohlorid | OtherNames = | Section1 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Identifikacija

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CAS broj

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• 191611-76-4 ^Y

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3D model (Jmol)

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• interaktivna slika

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SMILES

• OC1=CC=C(SCCC2CCCN2C)C=C1

|- | Section2 = ! colspan=2 style="background: #f8eaba; text-align: center;" |Svojstva

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Hemijska formula

| C₁₃H₁₉NOS

|- | Molarna masa

| 237,36 g·mol⁻¹

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SIB-1553A je agonist nikotinskih acetilholinskih receptora koji je selektivan za receptore sa β₄ podjedinicom. Administriranje SIB-1553A poboljšava memoriju i pažnju u modelu Parkinsonove bolesti.^[1]

Reference

1. Schneider, JS (2003). „The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys”. Journal of Pharmacology and Experimental Therapeutics. 306 (1): 401—6. PMID 12721323. doi:10.1124/jpet.103.051912. Приступљено 19. 12. 2011. 

Spoljašnje veze

• Portal Hemija