Dilazep

Dilazep
(IUPAC) ime
3-(43-[(3,4,5-trimetoksifenil)karboniloksi]propil1,4-diazepan-1-il)propil 3,4,5-trimetoksibenzoat
Klinički podaci
AHFS/Drugs.com Internacionalno ime leka
Identifikatori
ATC kod C01DX10
PubChem[1][2] 3074
ChemSpider[3] 2965
UNII F8KLC2BD5Z DaY
KEGG[4] D07843 DaY
ChEMBL[5] CHEMBL126075 DaY
Hemijski podaci
Formula C31H44N2O10 
Mol. masa 604,69 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Dilazep je vazodilatator koji deluje kao inhibitor adenozinskog preuzimanja.[6]

Reference

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  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  6. Hiroshi Deguchi, Hiroyuki Takeya, Hideo Wada, Esteban C. Gabazza, Nobuyuki Hayashi, Hajime Urano, and Koji Suzuki (1997-09-15). „Dilazep, an Antiplatelet Agent, Inhibits Tissue Factor Expression in Endothelial Cells and Monocytes”. Blood 90: 2345-2356. 

Spoljašnje veze

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