Kanabipiperidietanon

Kanabipiperidietanon
(IUPAC) ime
	2-(2-metoksifenil)-1-[1-([1-metilpiperidin-2-il]metil)indol-3-il]etanon
Klinički podaci
Identifikatori
CAS broj	1345970-43-5
ATC kod	nije dodeljen
ChemSpider	27330303
Hemijski podaci
Formula	C24H28N2O2
Mol. masa	376,490
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C24H28N2O2/c1-25-14-8-7-10-19(25)16-26-17-21(20-11-4-5-12-22(20)26)23(27)15-18-9-3-6-13-24(18)28-2/h3-6,9,11-13,17,19H,7-8,10,14-16H2,1-2H3 ; Key: AJSBNWAHEDVQJT-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Kanabipiperidietanon (1-(N-metilpiperidin-2-ilmetil)-3-(2-metoksifenilacetil)indol) je sintetički kanabinoid koji je sastojak biljnih mešavina sintetičkih kanabisa koji su u prodaju u Japanu, zajedno sa JWH-122 i JWH-081. Njegov afinitet vezivanja (IC₅₀) za kanabinoidne receptore je 591 nM na CB₁ i 968 nM na CB₂. On je 2,3 i 9,4 puta slabiji od JWH-250 na tim biološkim ciljevima.^[2]

Reference

↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Uchiyama N, Kikura-Hanajiri R, Goda Y (2011). „Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB₁ and CB₂ receptors”. Chemical & Pharmaceutical Bulletin 59 (9): 1203–5. PMID 21881274.

Povezano

Vanjske veze

	Portal Medicina
	Portal Hemija

[1] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[pmid21881274-2] Uchiyama N, Kikura-Hanajiri R, Goda Y (2011). „Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB₁ and CB₂ receptors”. Chemical & Pharmaceutical Bulletin 59 (9): 1203–5. PMID 21881274.

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[2]