CNST

CNST
Identifikatori
Aliasi	CNST
Vanjski ID-jevi	OMIM: 613439 MGI: 2445141 HomoloGene: 17139 GeneCards: CNST
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek)[1] Bend 1q44 Početak 246,566,444 bp[1] Kraj 246,668,595 bp[1]
Lokacija gena (miš) Hrom. Hromosom 1 (miš)[2] Bend 1|1 H4 Početak 179,373,935 bp[2] Kraj 179,455,043 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • phosphatase binding • GO:0001948, GO:0016582 vezivanje za proteine • connexin binding Ćelijska komponenta • integral component of membrane • trans-Golđijeva mreža • ćelijska membrana • Golđijev aparat • transport vesicle • membrana • GO:0016023 citoplazmatska vezikula • intracellular membrane-bounded organelle • GO:0009327 makromolekulani kompleks Biološki proces • negative regulation of phosphatase activity • positive regulation of Golgi to plasma membrane protein transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	163882	226744
Ensembl	ENSG00000162852	ENSMUSG00000038949
UniProt	Q6PJW8	Q8CBC4
RefSeq (mRNK)	NM_001139459 NM_152609	NM_146105
RefSeq (bjelančevina)	NP_001132931 NP_689822	NP_666217
Lokacija (UCSC)	Chr 1: 246.57 – 246.67 Mb	Chr 1: 179.37 – 179.46 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Konsortin (CNST) jest protein koji je kod ljudi kodiran genom CNST sa hromosoma 1.^[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 725 aminokiselina, a molekulska težina 79.597 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MDDSDTPTYY		LQIEPQDGCH		PGDSVERSVT		CLPSASDENE		NQLDGDGHEH
LTSSDSAMGK		PQVSEQDSLN		NNESCTLSCE		VAAGENLQNT		LCEASRDEQA
FLGKDKKIPG		KRSPRSKKGT		AKKIPPGLFS		GDIAPLMQEK		VLSAVTYAVD
DEEAAEVNAN		EQPEAPKLVL		QSLFSLIRGE		VEQLDSRALP		LCLHQIAESY
FQEEDYEKAM		KFIQLERLYH		EQLLANLSAI		QEQWETKWKT		VQPHTVTALR
NSEKGFNGED		FERLTKICAT		HQDPLLSKHK		IAAVEKSQER		KCSTQLLVSE
DPKEGGATTK		ESESKTCLGT		ESSKESQHTV		EPLGSSPCCH		QMDVQTDSPS
LSVTAGKDHM		EELLCSAEAT		LALHTQSSET		AGSPSGPDSS		EDACEDDSRL
QLAQTEACQD		VARIEGIAED		PKVFLSSKSK		TEPLISPGCD		RIPPALISEG
KYSQAQRKEL		RLPLRDASEA		LPTDQLENNE		LNELQQPDLT		DSDGKSPQAQ
ADSDGSENVL		CGNNQISDLG		ILLPEVCMAP		EEKGDKDDQL		NKETEDYLNS
LLEGCLKDTE		DSLSYEDNQD		DDSDLLQDLS		PEEASYSLQE		NLPSDESCLS
LDDLAKRIEI		AEVVPTEGLV		SILKKRNDTV		GDHPAQMQHK		PSKRRVRFQE
IDDSLDQDEV		GGGSCILLVL		LCIATVFLSV		GGTALYCTFG		DMESPVCTDF
ADNMDFYYTK		LLQGVAELKH		WIYLS

Reference

1. GRCh38: Ensembl release 89: ENSG00000162852 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038949 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. "Entrez Gene: C1orf71 chromosome 1 open reading frame 71".
7. "UniProt, Q6PJW8" (jezik: en.). Pristupljeno 9. 12. 2021.

Dopunska literatura

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.