G0S2

G0S2
Identifikatori
Aliasi	G0S2
Vanjski ID-jevi	OMIM: 614447 MGI: 1316737 HomoloGene: 7326 GeneCards: G0S2
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek)[1] Bend 1q32.2 Početak 209,675,412 bp[1] Kraj 209,676,390 bp[1]
Lokacija gena (miš) Hrom. Hromosom 1 (miš)[2] Bend 1 H6|1 97.69 cM Početak 192,954,469 bp[2] Kraj 192,955,525 bp[2]
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • molekularna funkcija Ćelijska komponenta • Lipidna kapljica • mitohondrija Biološki proces • positive regulation of extrinsic apoptotic signaling pathway • extrinsic apoptotic signaling pathway • GO:0097285 apoptoza • regulation of lipid metabolic process • positive regulation of cold-induced thermogenesis Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	50486	14373
Ensembl	ENSG00000123689	ENSMUSG00000009633
UniProt	P27469	Q61585
RefSeq (mRNK)	NM_015714	NM_008059
RefSeq (bjelančevina)	NP_056529	NP_032085
Lokacija (UCSC)	Chr 1: 209.68 – 209.68 Mb	Chr 1: 192.95 – 192.96 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

G0/G1 prekidač 2 jest protein koji je kod ljudi kodiran genom G0S2 sa hromosoma 1.^[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 103 aminokiseline, a molekulska težina 11.321 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
METVQELIPL		AKEMMAQKRK		GKMVKLYVLG		SVLALFGVVL		GLMETVCSPF
TAARRLRDQE		AAVAELQAAL		ERQALQKQAL		QEKGKQQDTV		LGGRALSNRQ
HAS

Reference

1. GRCh38: Ensembl release 89: ENSG00000123689 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000009633 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: G0/G1 switch 2". Pristupljeno 23. 3. 2016.
6. "UniProt, P27469" (jezik: en.). Pristupljeno 11. 12. 2021.

Dopunska literatura

• Zandbergen F, Mandard S, Escher P, Tan NS, Patsouris D, Jatkoe T, Rojas-Caro S, Madore S, Wahli W, Tafuri S, Müller M, Kersten S (2005). "The G0/G1 switch gene 2 is a novel PPAR target gene". Biochem. J. 392 (Pt 2): 313–24. doi:10.1042/BJ20050636. PMC 1316267. PMID 16086669.