This is a list of notable South Africans who are the subjects of Wikipedia articles.
- Elon Musk (b. 1971), Internet and space launch entrepreneur
- Harry Oppenheimer (1908–2000), businessman
- Mamphela Ramphele (b. 1947), political activist, academic, businesswoman and mother to the son of Steve Biko
- Cecil Rhodes (1853–1902), businessman
- Anderson Mann (1975) businessman, Founder of Voov
- Mark Shuttleworth (b. 1973), web entrepreneur, founder of Thawte and Ubuntu Linux, space tourist
See also: British Cape governors
- Pieter Willem Botha, 9th and last Prime Minister and 8th State President of South Africa
- Frederik Willem de Klerk (1916–2006), 9th and last State President of South Africa (1990–1994) and joint Nobel Peace Prize winner
- Paul Kruger (1825–1904), member of the Troika, 5th President of South African Republic
- Nelson Mandela (1918–2013), 1st democratically elected President of South Africa and joint Nobel Peace Prize winner
- Thabo Mbeki, 2nd post-apartheid President of South Africa
- Kgalema Motlanthe (born 1942), 3rd post-apartheid President of South Africa (born 1949)
- Jan Smuts (1870–1950), Boer general, British field marshal, 2nd and 4th Prime Minister of South Africa
- Johannes Strijdom (1893–1958), 6th Prime Minister of South Africa
- Jacob Zuma (born 1942), 4th post-apartheid President of South Africa
- Steve Nash, point guard for the Los Angeles Lakers (born 1974)
- Roger Federer, holds both Swiss and South African citizenship (born 1981)
- Paul Lloyd Jr, first South African wrestler to wrestle in WWE, son of successful SA wrestling promoter Paul Lloyd (born 1981)
- Taung Child, homonid fossil (born c. 2.5 million years ago)