MMPIP

MMPIP
(IUPAC) ime
	6-(4-metoksifenil)-5-metil-3-piridin-4-ilisoksazolo[4,5-c]piridin-4(5H)-on
Klinički podaci
Identifikatori
CAS broj	none
ATC kod	?
Hemijski podaci
Formula	C19H19N3O3
Mol. masa	337,372 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C19H19N3O3/c1-22-15(12-3-5-14(24-2)6-4-12)11-16-17(19(22)23)18(21-25-16)13-7-9-20-10-8-13/h3-10,15-17H,11H2,1-2H3 ; Key: DOWJYXHCYHWQSI-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

MMPIP je lek koji se koristi u naučnim istraživanjima. On deluje kao selektivni antagonist za podtip metabotropnog glutamatnog receptora mGluR₇.^[1] Ovaj podtip receptora učestvuje u responsu na kokain u mozgu.^[2]

Reference

↑ Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (October 2007). „In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists”. The Journal of Pharmacology and Experimental Therapeutics 323 (1): 147–56. DOI:10.1124/jpet.107.124701. PMID 17609420.
↑ Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (June 2009). „Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism”. Neuropsychopharmacology 34 (7): 1783–96. DOI:10.1038/npp.2008.236. PMID 19158667.

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