L-687,384

L-687,384
IUPAC ime
1'-benzylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]
Identifikatori
CAS broj95417-67-7 ДаY
ATC kodnone
PubChemCID 125328
Hemijski podaci
FormulaC21H25N
Molarna masa291.429 g/mol
  • c3ccccc3CN2CCC1(CC2)CCCc4c1cccc4

L-687,384 je agonist sigma receptora. On je selektivan za σ1 tip.[1] On je isto tako NMDA antagonist.[2]

  1. ^ Bergeron R, Debonnel G (1997). „Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors”. Psychopharmacology. 129 (3): 215—24. PMID 9084059. 
  2. ^ McLarnon J, Sawyer D, Church J (1994). „The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons”. Neuroscience Letters. 174 (2): 181—4. PMID 7526288.