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Methylpropyltryptamine

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Methylpropyltryptamine
Clinical data
Other namesMPT; N-Methyl-N-propyltryptamine
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • N-[2-(1H-indol-3-yl)ethyl]-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H20N2
Molar mass216.328 g·mol−1
3D model (JSmol)
  • CCCN(C)CCC1=CNC2=C1C=CC=C2
  • InChI=1S/C14H20N2/c1-3-9-16(2)10-8-12-11-15-14-7-5-4-6-13(12)14/h4-7,11,15H,3,8-10H2,1-2H3
  • Key:SZUNESAKJQIJAC-UHFFFAOYSA-N

Methylpropyltryptamine (MPT), also known as N-methyl-N-propyltryptamine, is a psychedelic drug of the tryptamine family. It is a homologue of methylethyltryptamine (MET).[1]

Use and effects

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In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin described MPT's effects as being unknown and its dose as being greater than 50 mg orally.[1]

Interactions

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See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Chemistry

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Detection

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An analytical method for MPT's detection has been reported.[2]

Crystal structure

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In 2019, Chadeayne et al. published the crystal structure of MPT.[3] The authors describe the structure as "...a single molecule in the asymmetric unit, with an indole group that demonstrates a mean deviation from planarity of 0.015 A°."

Analogues

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Analogues of MPT include 4-HO-MPT, 5-MeO-MPT, methylethyltryptamine (MET), ethylpropyltryptamine (EPT), ethylisopropyltryptamine (EiPT), and dipropyltryptamine (DPT), among others.[1]

Society and culture

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Canada

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MPT is not a controlled substance in Canada as of 2025.[4]

United States

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MPT is not an explicitly controlled substance in the United States.[5] However, it is an isomer of diethyltryptamine (DET), which is a schedule I controlled substance in this country, and so may be considered a controlled substance in the United States similarly.[5][6]

See also

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References

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  1. ^ a b c d Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  2. ^ Brandt SD, Freeman S, Fleet IA, Alder JF (September 2005). "Analytical chemistry of synthetic routes to psychoactive tryptamines. Part III. Characterisation of the Speeter and Anthony route to N,N-dialkylated tryptamines using CI-IT-MS-MS". The Analyst. 130 (9): 1258–1262. Bibcode:2005Ana...130.1258B. doi:10.1039/b504001a. PMID 16096671.
  3. ^ Chadeayne AR, Golen JA, Manke DR (2019-07-28). "N -Methyl- N -propyltryptamine (MPT)". IUCrData. 4 (7) x190962. Bibcode:2019IUCrD...490962C. doi:10.1107/S2414314619009623. ISSN 2414-3146.
  4. ^ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  5. ^ a b Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
  6. ^ Drug Enforcement Administration (3 December 2007). "Definition of "Positional Isomer" as It Pertains to the Control of Schedule I Controlled Substances". Federal Register.
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