5-Benziloksitriptamin

5-Benziloksitriptamin
IUPAC ime
2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
Identifikatori
CAS broj20776-45-8
PubChemCID 89576
ChemSpider80845 ДаY
Hemijski podaci
FormulaC17H18N2O
Molarna masa266.34 g/mol
  • NCCC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C21
  • InChI=1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2 ДаY
  • Key:WKPDXBXNJWWWGQ-UHFFFAOYSA-N ДаY

5-Benziloksitriptamin (5-BT) je derivat triptamina koji deluje kao agonist 5-HT1D, 5-HT2 i 5-HT6 serotoninskih receptora.[1][2][3][4]

Vidi još

[уреди | уреди извор]

Literatura

[уреди | уреди извор]
  1. ^ Lyon RA, Titeler M, Seggel MR, Glennon RA (1988). „Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens”. European Journal of Pharmacology. 145 (3): 291—7. PMID 3350047. doi:10.1016/0014-2999(88)90432-3. 
  2. ^ Peroutka SJ, McCarthy BG, Guan XM (1991). „5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent”. Life Sciences. 49 (6): 409—18. PMID 1650872. doi:10.1016/0024-3205(91)90582-V. 
  3. ^ Cohen ML, Schenck K, Nelson D, Robertson DW (1992). „Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins”. European Journal of Pharmacology. 211 (1): 43—6. PMID 1319907. doi:10.1016/0014-2999(92)90260-B. 
  4. ^ Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). „Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells”. Neuropharmacology. 36 (4-5): 713—20. PMID 9225298. doi:10.1016/S0028-3908(97)00019-1.