Aknadinine

Aknadinine

Names
Other names 4-demethylhasubanonine[1]
Identifiers
CAS Number	24148-86-5^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:229137
ChEMBL	ChEMBL1098359
ChemSpider	140631
PubChem CID	159966
UNII	V5XGU77PZ9^Y
InChI InChI=1S/C20H25NO5/c1-21-10-9-19-11-13(22)17(25-3)18(26-4)20(19,21)8-7-12-5-6-14(24-2)16(23)15(12)19/h5-6,23H,7-11H2,1-4H3/t19-,20+/m0/s1 Key: XLWYWPDYNLZUJS-VQTJNVASSA-N
SMILES CN1CC[C@@]23[C@@]1(CCC4=C2C(=C(C=C4)OC)O)C(=C(C(=O)C3)OC)OC
Properties
Chemical formula	C20H25NO5
Molar mass	359.42
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Aknadinine (also known as 4-demethylhasubanonine^[1]) is an opioid alkaloid isolated from members of the genus Stephania (Stephania cepharantha^[2] and Stephania hernandifolia.^[3]). Structurally it is a member of the hasubanan family of alkaloids and features an isoquinoline substructure.

See also

• Hasubanonine

References

1. Moza, B.K.; B. Bhaburi; D.K. Basu; J. Kunitomo; Y. Okamoto; E. Yuge; Y. Nagai; T. Ibuka (1970). "Constitution of three new alkaloids, aknadinine (4-demethylhasubanonine), aknadicine (4-demethylnorhasubanonine), and aknadilactam (4-demethyl-16-oxohasubanonine)". Tetrahedron. 26 (2): 427–433. doi:10.1016/S0040-4020(01)97839-1. ISSN 0040-4020.
2. He, L; Zhang, YH; Tang, LJ; Song, SH; Sun, QY (October 2010). "[Study on the alkaloids in the stems and leaves of Stephania cepharantha (II)]". Zhong Yao Cai (in Chinese). 33 (10): 1568–1570. PMID 21355192.
3. Kupchan, SM; Suffness, MI; White, DN; McPhail, AT; Sim, GA (1968). "The isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia". Journal of Organic Chemistry. 33 (12): 4529–32. doi:10.1021/jo01276a052. PMID 5743784.