Dipyanone

Not to be confused with dipyrone.

Dipyanone

Identifiers
IUPAC name 4,4-diphenyl-6-(1-pyrrolidinyl)-heptan-3-one
CAS Number	60996-94-3^Y
PubChem CID	57483648
ChemSpider	128910076
UNII	P8UN8D5PUN
CompTox Dashboard (EPA)	DTXSID401336888
Chemical and physical data
Formula	C23H29NO
Molar mass	335.491 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCC(=O)C(CC(C)N1CCCC1)(c1ccccc1)c1ccccc1
InChI InChI=1S/C23H29NO/c1-3-22(25)23(20-12-6-4-7-13-20,21-14-8-5-9-15-21)18-19(2)24-16-10-11-17-24/h4-9,12-15,19H,3,10-11,16-18H2,1-2H3 Key:LJIUPFDRFKFNJE-UHFFFAOYSA-N

Dipyanone is an opioid analgesic which has been sold as a designer drug, first identified in Germany in 2021.^[1][2] It is closely related to medically used drugs such as methadone, dipipanone and phenadoxone, but is slightly less potent.^[3][4][5]

See also

• Desmethylmoramide
• IC-26
• Nufenoxolea
• Pyrrolidinylthiambutene
• R-4066

References

1. European Monitoring Centre for Drugs and Drug Addiction. (June 2022). New psychoactive substances: 25 years of early warning and response in Europe. An update from the EU Early Warning System (PDF). European Monitoring Centre for Drugs and Drug Addiction. doi:10.2810/882318 (inactive 12 July 2025). ISBN 978-92-9497-737-3.
2. Vandeputte MM, Walton SE, Shuda SA, Papsun DM, Krotulski AJ, Stove CP (September 2023). "Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs". Analytical and Bioanalytical Chemistry. 415 (21): 5165–5180. doi:10.1007/s00216-023-04722-7. PMID 37173408.
3. Ofner P, Walton E (1950). "444. Search for new analgesics. Part IV. Variations in the basic side-chain of amidone". Journal of the Chemical Society (Resumed): 2158. doi:10.1039/JR9500002158.
4. Lenz GR, Evans SM, Walters DE, Hopfinger AJ (1986). Opiates. Academic Press. pp. 406–407. ISBN 978-0-12-443830-9.
5. Berardinelli D, Kutzler J, Taoussi O, Zaami S, Pichini S, Basile G, et al. (June 2025). "Dipyanone, a new methadone-like synthetic opioid: In vitro and in vivo human metabolism and pharmacological profiling". Archives of Toxicology. 99 (6): 2339–2353. Bibcode:2025ArTox..99.2339B. doi:10.1007/s00204-025-04023-1. PMC 12185669. PMID 40295323.