5-Benziloksitriptamin

5-Benziloksitriptamin
(IUPAC) ime
2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
Klinički podaci
Identifikatori
CAS broj 20776-45-8
ATC kod ?
PubChem[1][2] 89576
ChemSpider[3] 80845
Hemijski podaci
Formula C17H18N2O 
Mol. masa 266.34 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

5-Benziloksitriptamin (5-BT) je derivat triptamina koji deluje kao agonist 5-HT1D, 5-HT2 i 5-HT6 serotoninskih receptora.[4][5][6][7]

Povezano

[uredi | uredi kod]

Literatura

[uredi | uredi kod]
  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). „Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens”. European Journal of Pharmacology 145 (3): 291–7. DOI:10.1016/0014-2999(88)90432-3. PMID 3350047. 
  5. Peroutka SJ, McCarthy BG, Guan XM (1991). „5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent”. Life Sciences 49 (6): 409–18. DOI:10.1016/0024-3205(91)90582-V. PMID 1650872. 
  6. Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). „Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins”. European Journal of Pharmacology 211 (1): 43–6. DOI:10.1016/0014-2999(92)90260-B. PMID 1319907. 
  7. Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ (1997). „Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells”. Neuropharmacology 36 (4-5): 713–20. DOI:10.1016/S0028-3908(97)00019-1. PMID 9225298.