Thienodiazepine

The core structure of thienodiazepines

Not to be confused with thienobenzodiazepine or thienotriazolodiazepine.

A thienodiazepine^[1] is a heterocyclic compound containing a diazepine ring fused to a thiophene ring.

If R₁ and R₂ are part of a triazole ring, the substance is called a "thienotriazolodiazepine."

The thienodiazepine structure forms the central core of some pharmaceutical and recreational drugs, including etizolam, bentazepam, clotiazepam, and tofisopam.

Since thienodiazepines interact with the benzodiazepine receptor site, they typically have similar effects as benzodiazepines.

References

1. PubChem. "Thienodiazepine". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-11-25.